Symptoms after vulvar cancer spread
summary
Vulvar cancer is a malignant tumor of vulva, which is not rare, accounting for about 5% of female genital tract malignant tumors. Among them, primary squamous cell carcinoma is the main one, and secondary malignant tumor is rare. Most often occurs in the labia major, followed by the labia minor, vaginal vestibule and clitoris. First, local nodules or masses, and gradually increased, necrosis, ulceration and infection, increased secretion, accompanied by itching pain. The tumor may be papillary or vegetable like, and may expand rapidly, involving anus, rectum and bladder. Let's talk about the symptoms after vulvar cancer spread
Symptoms after vulvar cancer spread
1. Growth site: about 2 / 3 lesions occurred in the labia major, 1 / 3 in the labia minor, clitoris or syndesmosis. Most of the lesions occurred in the anterior part of the vulva, and a few occurred in the perineum or the lateral surface of the labia major. Intraepithelial carcinoma mainly occurs in the labia major. Adenocarcinoma occurs in the paraurethral gland or vestibular gland.
2. General view: ① squamous cell carcinoma can be manifested as simple ulcer, white lesion, subcutaneous mass or polypoid lesion. In the early stage, the epithelial foot of the epidermis infiltrates into the stroma and gradually forms a subcutaneous nodule. This nodule can also break and become smaller, which is misdiagnosed as inflammation. In the late stage, it develops into vegetable pattern vegetation or ulcer. ② Bowen's disease is characterized by dark red rough spots, clear and irregular boundary, scab on the surface, granulation tissue and exudation surface after scab removal. Paget's disease showed eczema like changes, red, slightly protruding, accompanied by white lesions or small particles, sometimes with shallow ulcer formation and scab.
3. Microscopic: ① squamous cell carcinoma, most of them well differentiated, often with the formation or keratinization of epithelioid beads; However, the clitoris or vestibule were not well differentiated. In addition, nucleic acid synthesis was also found in the adjacent normal tissues, which indicated that it was necessary to remove the whole vulva in the treatment of vulvar cancer; ② Bowen's disease is characterized by hyperkeratosis and dyskeratosis of epidermis, hyperplasia of spinous layer, disorder of cell arrangement, deep and abnormal nuclear staining, and intact basement membrane of epidermis. There are typical Paget's cells deep in the epidermis, which are large in volume, round, oval or polygonal in shape. The cytoplasm is empty and transparent. The basement membrane of the epidermis is complete. However, the tumor cells often involve more than the edge of the lesion. The diagnosis of Paget's disease should pay attention to subepithelial sweat gland carcinoma; ③ Adenocarcinoma, with gland hyperplasia, epithelial multilayer, arranged disorderly, nuclear staining deep and abnormal.
matters needing attention
Develop good habits, quit smoking and limit alcohol. Smoking, the World Health Organization predicted that if people no longer smoke, five years later, the world's cancer will reduce 1 / 3; Second, don't drink too much. Tobacco and alcohol are extremely acidic substances. People who smoke and drink for a long time can easily lead to acidic constitution. Don't eat too much salty and spicy food, don't eat too hot, too cold, expired and deteriorated food; The old and frail or those with certain disease genetic genes should eat some anti-cancer food and alkaline food with high alkali content to maintain a good mental state. Have a good attitude to deal with pressure, work and rest, do not fatigue. It can be seen that stress is an important cause of cancer. Traditional Chinese medicine believes that stress leads to overwork and body deficiency, which leads to the decline of immune function, endocrine disorders, metabolic disorders in the body, leading to the deposition of acid substances in the body; Pressure can also lead to mental tension, causing qi stagnation, blood stasis, toxic fire, etc. Strengthen physical exercise, strengthen the physique, more exercise in the sun, more sweating can be acid substances in the body with sweat out of the body, to avoid the formation of acid constitution.
