Severe erythema multiforme?

summary

Erythema multiforme is an acute inflammatory skin disease with self limiting, rash, polymorphic, erythematous papules, and wind blister. The characteristic lesions are target lesion and Irid rash, varying degrees, mucosal lesions, and a few visceral lesions. The incidence of this disease is slightly higher in spring and autumn than in women. The highest incidence rate is 10-30 years old, and 20% of them are adolescents. Severe erythema multiforme? Now let me tell you something.

Severe erythema multiforme?

Drugs can also cause erythema multiforme, such as antibiotics, anticonvulsants, aspirin, antituberculous drugs, antifungal drugs and so on. The common sensitizing drugs are sulfonamides, penicillins, non hormonal anti-inflammatory drugs, antiepileptic drugs and so on. Visceral diseases, such as connective tissue disease, vasculitis, non Hodgkin's lymphoma, leukemia, multiple myeloma, etc.

The first cause of erythema multiforme is infection. Bacteria, Rickettsia, mycoplasma, spirochetes, chlamydia, viruses, fungi, parasites and other infections are possible, simple cytomegaly infection is the most common. Contact materials such as primrose, ivy, capsaicin, rosin, formaldehyde.

Benzopyrene and other polymorphs have typical target lesions, which are distributed symmetrically at the ends of extremities, with mucosal lesions. Severe patients have systemic symptoms such as fever. There are some keratinocytes necrosis in histopathology. When combined with HSV infection, the detection of HSV antigen in skin lesions is positive.

matters needing attention

Skin lesions should be protected with cleaning, antipruritic, mild anti-inflammatory agents. Such as vegetable oil, calamine lotion, zinc oxide oil, silicone oil cream, glucocorticoid ointment, etc. The function system should be used to keep the oral cavity clean and the eye lesions should be consulted as soon as possible.