Myasthenia gravis

summary

I am a patient with myasthenia gravis. The muscle strength of ilium is normal, and it is difficult to swallow. Now the symptoms are getting worse year by year. After treatment, I have basically recovered. Now I would like to share with you the problems about myasthenia gravis.

Myasthenia gravis

Treatment 1: corticosteroids are commonly used. It can be treated with high-dose pulse therapy, such as prednisone, or with high-dose methylprednisolone. After the symptoms are improved, gradually reduce the dosage, and then use the maintenance dosage. The medication can last for several years. This method is suitable for severe patients. At the beginning of medication, the symptoms may worsen, which should be observed. Hormone therapy is effective for most patients, can alleviate the condition for several months to several years, some patients can gradually stabilize the condition. If the hormone effect is not good, cyclophosphamide and azathioprine can be considered.

Treatment 2: hormone or immunosuppressive therapy. The patients over 35 years old with poor therapeutic effect or continued deterioration can be treated with thymectomy regardless of thymic tumor. Most patients have good curative effect after operation.

Treatment 3: the difference between myasthenic crisis and cholinergic crisis should be distinguished first in crisis management. If it is difficult to distinguish between myasthenic crisis and cholinergic crisis, epenol ammonium chloride can be used, but assisted breathing should be prepared. If the symptoms worsen, it is cholinergic crisis, and atropine should be injected immediately. If it is myasthenic crisis, neostigmine can be injected, combined with ephedrine and potassium chloride.

matters needing attention

This disease needs to pay attention to: exercise to enhance physical fitness, but not excessive exercise, especially in children with myasthenia gravis, excessive exercise will aggravate the symptoms, so patients should choose some sports that help to restore health according to their own situation. Patients with severe illness or long-term bedridden patients should be given appropriate massage to prevent pressure sores.