What reason is coagulation fast

Update Date: Source: Network

summary

As far as I know, the causes of disseminated intravascular coagulation are various and complex, but most of them are caused by surgery or severe trauma. Generally, such diseases will not occur, so we can rest assured.

What reason is coagulation fast

First, bacteria, viruses, spirochetes, hyperthermia, antigen antibody complexes, continuous ischemia in shock, hypoxia and acidosis, bacterial endotoxin in septicemia, etc. can damage vascular endothelial cells under certain conditions and cause disseminated intracellular coagulation.

Second: in the case of major surgery, severe trauma, obstetric accidents (such as placental abruption, intrauterine stillbirth, etc.), malignant tumor or necrosis of substantive organs, there are serious tissue damage or necrosis, so a large number of procoagulant substances into the blood, leading to the start of coagulation mechanism.

Third: acute hemolysis, a large number (> 50ml) of blood transfusion, drug-induced immune hemolysis, the formation of antigen antibody complex leads to a large number of destruction of red blood cells, resulting in disseminated intravascular coagulation.

matters needing attention

People with coagulation disorders often have skin or mucous membrane bleeding, such as gingival bleeding, ecchymosis, menorrhagia, and hematemesis and melena in severe cases.