Can pulmonary hypertension be cured

summary

Pulmonary hypertension is a kind of disease that many people will encounter now. Many people want to know whether pulmonary hypertension can be cured. This disease is not well treated now, and it can only play a role in alleviating, so we need to know how to prevent pulmonary hypertension. Today I will introduce the performance of pulmonary hypertension and the prevention of pulmonary hypertension.

Can pulmonary hypertension be cured

First: prostacyclins: prostacyclin (PGI2) is a physiological product of arachidonic acid metabolism, mainly synthesized by vascular endothelium, which dilates pulmonary vessels and inhibits pulmonary vascular remodeling. It can reduce pulmonary artery pressure and pulmonary vascular resistance, increase cardiac output and six minute walking distance, improve quality of life and prolong survival time. There are many forms of prostacyclins: epopsoetenol, benapnost (listed in China), treprostinil, iloprost (atomized form of vitamin C has been listed in China). Iloprost is a stable prostacyclin analogue with a serum half-life of 20-25 minutes. It is atomized (2.5-5 / time, 6-9 times / day in the mouthpiece). Inhalation: the hemodynamic effect lasts for 30-90 minutes. Minor side effects: cough, flushing, headache.

Second: endothelin receptor antagonist (ETA): endothelin (ET-1) is one of the important causes of pulmonary hypertension. Era has the effects of dilating pulmonary vessels, anti proliferation and improving endothelial function. Clinical application can improve the activity tolerance and prolong the survival time of patients. There are two different receptors for et: ETA and ETB. Bosentan bosentan (traceer?): non selective receptor antagonist, which has been listed in China. The main side effects of selective ETA were abnormal liver function, anemia and teratogenicity.

Third: PDE5: selectively inhibit PDE5 (a large number of expression in the lung), increase cGMP concentration in smooth muscle cells, relax vascular smooth muscle, expand pulmonary artery, reduce pulmonary vascular resistance, so as to reduce pulmonary artery pressure and increase activity tolerance. Sildenafil, Viagra, vardenafil, 5 mg, bid, tadalafil.

matters needing attention

Pulmonary hypertension is an extremely malignant disease. More than 70% of the patients are young people. Almost everyone knows that the prognosis of cancer is poor, but no one knows that pulmonary hypertension is an extremely malignant disease, and its prognosis is catastrophic. It can be said that this disease is cancer in cardiovascular disease.