Symptoms of plague

summary

Plague is an infectious disease. It spreads by droplet transmission, wound infection and rat fleas bite. Incidence rate is high, also known as the black death. The fatality rate of plague is high. Therefore, we should know more about the disease and prevent it as soon as possible, so as to avoid regret after being infected with Yersinia pestis. To understand the disease, we should first understand the etiology, and then understand the symptoms. What is the cause of plague, the symptom of plague? Let's talk about it

Symptoms of plague

The incubation period of plague is very short, most of them are 2-3 days, and individual cases can reach 9 days. The initial symptoms and signs were fever, chills, discomfort, head and limb pain, nausea, and sore throat. Lymphadenitis was found in the lymph nodes where the fleas were first bitten. The affected lymph nodes were fever, swelling, redness, softening, and suppuration.

Acute onset, high fever and chills, body temperature rapidly reaching 39 ℃ - 40 ℃, severe headache, nausea and vomiting, accompanied by restlessness, blurred consciousness, arrhythmia, decreased blood pressure, shortness of breath, skin and mucous membrane bleeding spots, followed by massive bleeding and accompanied by melena, hematuria. At the same time or a little before the symptoms appeared, lymph nodes were swollen (most in the groin). In typical cases, lymph nodes were tender, hard, with swelling of surrounding tissues.

The skin surface is smooth, red but not hot. Most of the patients had dysphoria, delirium, delirium and ataxia. It is easy for doctors to touch the swollen liver and spleen during physical examination. The lymph nodes can be filled with pus and break up in the second week. If not treated, more than 60% of the patients died, and most of the deaths occurred between the third and fifth day of the disease.

matters needing attention

When vaccination begins to spread among rats, the residents in and around the epidemic area and the staff entering the epidemic area should be vaccinated. It is commonly used as EV non-toxic strain dry live vaccine, which is inoculated by skin scratch method, that is, 2 drops of bacteria solution, 3-4cm apart. The mice were immunized after 2 weeks. The current vaccine still can not produce long-term immune protection against bubonic plague and pneumonic plague. Therefore, it is generally vaccinated once a year, and if necessary, it will be vaccinated again after 6 months. The F1 antibody produced by the newly developed 06173 vaccine was twice as effective as that produced by EV strain.