What does hemolysis complete set include

summary

In the case of hemolytic disease with incompatibility of maternal and fetal blood group, a complete set of hemolytic examination should be carried out to make clear the specific situation, so as to determine the subsequent countermeasures. Let's take a look at the hemolysis package.

What does hemolysis complete set include

First: peripheral blood routine. The red blood cell count and hemoglobin content were decreased, and broken red blood cells and abnormal red blood cells could be seen in the blood smear. Typical abnormal red blood cells or self agglutination phenomenon can provide some clues for hemolysis examination.

Secondly, the significance of determination of plasma free hemoglobin. There is only a trace of free hemoglobin in normal plasma. 40 mg / L is an important indicator of hemolysis, especially intravascular hemolysis, such as paroxysmal nocturnal hemoglobinuria, blood group incompatibility and transfusion reaction. Extravascular hemolysis, such as hereditary spherocytosis, generally does not increase.

Finally: red blood cell longevity test is a reliable index to detect hemolysis. 51Cr, 3p-dfp or diisopropylfluorophosphate labeled red blood cell method can reflect the index of red blood cell longevity. This test showed that the life span of red blood cells was shortened, indicating hemolysis.

matters needing attention

If the pregnant mother's blood type is O type, and the father is not o type blood, in this case is more prone to hemolytic disease of the newborn, to do a good job in pregnancy examination, once found abnormal to timely treatment.