Initial symptoms of 4S syndrome?

summary

Staphylococcal skin scald like syndrome (SSSS) has been called neonatal exfoliative dermatitis, staphylococcal toxic epidermolysis, bacterial toxic epidermolysis and Ritter's disease. This disease is a kind of severe acute generalized exfoliative pustulosis in the newborn. It is characterized by flabby scald like bullae and large epidermis exfoliation on the basis of generalized erythema. Most of them occur in infants and occasionally in adults. Initial symptoms of 4S syndrome? Let's talk about it

Initial symptoms of 4S syndrome?

The disease usually occurs in infants 1-5 weeks after birth, occasionally in adults. The onset of the disease is sudden. At the beginning, erythema occurs around the mouth or eyelids, and then quickly spreads to the trunk and the proximal extremities, and even the whole body. There is obvious tenderness in the lesions. Loose bullae occurred on the basis of erythema, exudation and scab appeared around the mouth and eyelids within 1-2 days, and a large amount of scab fell off, leaving radial cracks around the mouth.

The epidermis of other parts is wrinkled and rubbed with a little force, that is, there is a large area of epidermis exfoliated, showing a bright red, edematous and erosive surface, that is, Nissl sign is positive, similar to scald. At the edge of the erosion, the epidermis is loose and curly, and the skin of hands and feet can be peeled off like gloves or socks. After that, the peeled off part gradually turns from bright red to purplish red, dark red, no longer peeled off, and appears chaff like desquamation. After 7-14 days, it is cured.

Oral, nasal mucosa, conjunctiva can be affected, stomatitis, rhinitis and corneal ulcer. Patients are often accompanied by fever, anorexia, vomiting, diarrhea and other systemic symptoms. Some died of secondary bronchopneumonia, sepsis, abscess or gangrene, mostly in infants and young children.

matters needing attention

1. Pay attention to the baby's cleanliness, diapers should be clean, and medical staff or family members with purulent skin disease should not contact with the newborn. 2. Strengthen nursing and keep warm. Pay attention to oral and eye care. 3. Sufficient and effective antibiotics should be used in the early stage to eliminate the infection focus of Staphylococcus aureus and stop the production of bacterial toxin. In order to select suitable antibiotics, antibiotic sensitivity test was carried out.