How to rescue and treat barbiturates poisoning?

summary

Barbiturates can be divided into long-term, medium, short-term and ultra short-term effects. Acute poisoning can be caused when the hypnotic dose of this kind of drugs is 5-10 times. So how to rescue barbiturates poisoning? Now please come to Baibai safety net to learn the first aid methods of drug poisoning.

How to rescue and treat barbiturates poisoning?

Patients with oral drug poisoning should induce vomiting and gastric lavage as soon as possible (gastric lavage should be done after more than 5-6 hours, so the drug can cause pyloric spasm and stay in the stomach for a long time). It is forbidden to induce vomiting in comatose patients. Gastric lavage should also be carried out carefully to avoid inhaling trachea. Gastric lavage solution can be 1:5000 potassium permanganate solution, normal saline or light saline. After gastric lavage, gavage with activated carbon suspension or general antidote, and give sodium sulfate catharsis (avoid magnesium sulfate, in order to prevent aggravating central inhibition). If it is caused by enema, enema should be done.

Intravenous drip of 10% glucose solution and normal saline half (appropriate potassium). If the urine is not alkaline, appropriate amount of 5% sodium bicarbonate solution can be added into the infusion. The application of 20% mannitol or 25% sorbitol by intravenous injection or rapid drip, as well as furosemide, diuretic acid or other diuretics can accelerate the elimination of poisons.

Severe patients can be treated with hemodialysis or peritoneal dialysis, and infants can be treated with exchange transfusion. Since the excretion of barbital in alkaline urine is increased, the pH of urine should be checked frequently. When the urine is not alkaline, 5% sodium bicarbonate 5ml / kg can be injected intravenously; Or oral acetazolamide 5mg / kg, 3 times a day, make urine alkaline. If the patient's symptoms begin to improve in the process of alkalization of urine, and then appear acidosis with accelerated breathing, it is suggested that pulmonary edema (Huck's lung) occurs, and dialysis or blood perfusion should be used for treatment.

matters needing attention

Pay attention to keep warm and keep respiratory tract unobstructed. For children with weak breathing or dyspnea, it is very important to give oxygen immediately and carry out artificial assisted respiration. When respiratory paralysis occurs, artificial respiration should be insisted on. If necessary, endotracheal intubation and pressure oxygen should be given. The children with shock or dehydration should be treated with infusion, blood transfusion, and pressor drugs such as dopamine and cardiotonic.