Grade 4 glioma symptoms?

summary

Glioma is the most common type of brain tumor. According to the cell composition, it can be divided into astroblastoma, astrocytoma, glioblastoma multiforme, oligodendroglioma, neuroblastoma, ependymoblastoma, ependymoma and so on. The growth site and malignant degree of these tumors are different. Malignant glioma is a common type of brain tumor in clinic. Its incidence rate is 60% in brain tumors. Grade 4 glioma symptoms? Let's talk about it

Grade 4 glioma symptoms?

The symptoms and signs caused by glioma mainly depend on the space occupying effect and the function of the affected brain regions. Glioma can cause headache, nausea and vomiting, epilepsy, blurred vision and other symptoms due to its space occupying effect. In addition, because of its influence on the function of local brain tissue, it can also make patients have other symptoms.

For example, optic glioma can lead to the loss of vision; Spinal gliomas can cause limb pain, numbness and muscle weakness; Gliomas in the central region can cause motor and sensory disturbance; Gliomas in the language area can cause difficulties in language expression and understanding. Because of the different malignant degree of glioma, the speed of symptoms is also different.

For example, patients with low-grade gliomas often have a history of several months or even last year, while patients with high-grade gliomas often have a history of several weeks to several months. According to the patient's history, symptoms and signs, we can preliminarily infer the location of the lesion and the degree of malignancy.

matters needing attention

Chemotherapy and targeted therapy play an important role in the treatment of glioma. For high-grade gliomas, temozolomide can significantly prolong the survival and prognosis of patients. At present, temozolomide is the only chemotherapy drug with definite curative effect in the treatment of glioma. For newly diagnosed high-grade glioma patients, temozolomide should be taken alone for a period of time (6-12 cycles) after concurrent radiotherapy (concurrent chemoradiotherapy). Other chemotherapy drugs (such as nimustine) may be effective in the treatment of recurrent glioma. Avastin, a new vascular targeting drug, has a definite curative effect on recurrent high-grade glioma and can significantly prolong the survival of patients.