What is Miller Fisher syndrome?

summary

Miller Fisher syndrome is one of the differential diagnoses of the syndrome. It is a common disease of nerve root inflammation and brain stem inflammation after infection. Patients will have dyskinesia, ophthalmoplegia and other symptoms. Most of the patients with Miller Fisher syndrome have the symptoms of prodromal infection one week before the onset, and the upper respiratory tract infection is the main. Vibrio jejuni is one of the most common associated pathogens. What is Miller Fisher syndrome? Now let me tell you something.

What is Miller Fisher syndrome?

In 90% of cases, the degree of muscle weakness reaches the peak within 3 weeks. The symptoms of muscle weakness are always more significant than sensory symptoms or signs, In severe cases, more than 50% of patients have weakness of facial and oropharyngeal muscles, and 5% ~ 10% of patients need tracheal intubation due to respiratory failure. In severe cases, autonomic nervous system dysfunction (including blood pressure fluctuation) and inappropriate secretion of antidiuretic hormone may occur, Arrhythmia, pupil changes, respiratory paralysis and autonomic nerve dysfunction can be life-threatening. About 5% of cases died.

Once the function of the upper brain nucleus is abnormal, the patient will have oculomotor paralysis or dyskinesia. If the lower brain nucleus is damaged, there will be dysphagia. 40% of patients with Miller Fisher syndrome had dysphagia during illness.

Usually, the symptoms of neuritis and infection will be separated by about one to two weeks. In severe cases, the whole body will even be weak and respiratory failure will occur. It is necessary to rely on artificial respiration for a living, but it may be only mild symptoms[ 1] Most of the patients are optimistic about their disease expectations. In most cases, patients begin to recover in the first 2 to 4 weeks of treatment, and may even recover completely within 6 months. Some patients will have a slight disability. Less recurrence

matters needing attention

The disease can be caused by a bacterial infection. In addition, there will be general muscle weakness and coordination disorders. Most individuals with the disease develop unique antibodies against the disease. The National Institute of nervous system diseases actively supports research on new methods of diagnosis, treatment and final cure for patients with Miller Fisher syndrome. So find that you may have Miller Fisher syndrome, please go to the hospital in time for treatment