Can polygenic diseases be cured?

summary

In recent years, with the development of modern medicine, medical genetics workers are familiar with the pathogenesis of some genetic diseases in the study of genetic diseases, which provides a certain basis for the treatment and prevention of genetic diseases, and constantly puts forward new treatment measures. Can polygenic diseases be cured? Now let me tell you something.

Can polygenic diseases be cured?

Diet treatment of some genetic diseases can prevent the occurrence of diseases by controlling diet, so as to receive therapeutic effect. For example, the pathogenesis of phenylketonuria is phenylalanine hydroxylase deficiency, so that phenylalanine and Phenylpyruvate accumulate in the body and cause disease, can appear in children with mental retardation or become an idiot. However, if the diagnosis is accurate, it is better to start prevention and treatment in the early 7-10 days after birth. Within 3 months after birth, giving children a low phenylalanine diet, such as rice, Chinese cabbage, spinach, potato, mutton and so on, can promote the normal growth and development of infants.

Drug therapy drugs often play an auxiliary role in the treatment of genetic diseases, so as to improve the condition of patients and reduce pain. It is mainly symptomatic treatment, such as taking analgesics to relieve pain. It can also improve the metabolism of the body, such as hepatolenticular degeneration, mainly due to the disorder of copper metabolism in the body, so that the level of copper in the blood increases, leading to fetal malformation. In order to maintain the normal level of copper in the body, we can take drugs to promote the excretion of copper, and limit the consumption of food containing copper, so as to achieve good therapeutic effect. Some diseases, such as congenital hypoimmunoglobulinemia, can be treated by injection of immunoglobulin preparation.

Surgical treatment surgical correction refers to the use of surgical resection of some organs or some organs with morphological defects for surgical repair. For example, in spherocytosis, due to genetic defects, the osmotic fragility of red blood cell membrane is significantly increased, and the red blood cells are spherical. This kind of red blood cells are easily destroyed when passing through the splenic sinuses of the spleen, resulting in hemolytic anemia. Splenectomy can be carried out, although splenectomy can not change the abnormal morphology of red blood cells, but it can prolong the life of red blood cells and obtain therapeutic effect. For polydactyly, cleft lip and genitalia deformity, it can be corrected by operation. Another example, body odor is also a genetic disease, but as long as the patient's axillary secretion excessive glands gouged out, can eliminate the patient.

matters needing attention

For a large number of genetic diseases that can not be cured, we should take positive measures, focusing on the prevention of genetic diseases. The prevention of genetic diseases is mainly to reduce or eliminate the occurrence and spread of genetic diseases through artificial methods. We should also strengthen genetic counseling, popularize the knowledge of genetic diseases, take preventive measures to detect the carriers of pathogenic genes, so as to avoid or reduce the birth of children with genetic diseases.