Why clone

summary

Crohn's disease is a very common disease, often ileum and right colon lesions, which can seriously affect the daily life of patients. So what causes Crohn's disease? Now let's take a look.

Why clone

One reason: environmental factors: the incidence rate of urban residents is higher than that of rural population. This difference exists in Sweden, which has high health care level in rural areas, which may be related to social and economic status.

The second reason is familial inheritance. A large number of data show that Crohn's disease is related to genetic factors. It was found that the concordance rate of Crohn's disease among monozygotic twins was 67%, while that among dizygotic twins was only 8%. At the same time, it was found that there was inconsistency between Crohn's disease patients and their spouses, and there was no difference between them and the general population.

Cause 3: infection factor: in the early years, because the pathological manifestations of Crohn's disease were similar to those of non calcified tuberculosis, it was suspected that the disease was caused by Mycobacterium tuberculosis, but the pathogen could not be isolated by various methods. It was found that the mice inoculated with these mycobacteria could produce granuloma in liver and spleen and acid fast bacilli. After oral administration of these acid fast bacilli to suckling sheep, non caseous granuloma may occur in the terminal ileum of the sheep a few months later. It is suggested that Mycobacterium may be the cause of Crohn's disease.

matters needing attention

The general supportive and symptomatic treatment of this disease is very important. Strengthen nutrition, correct metabolic disorder, improve anemia and hypoalbuminemia. If necessary, blood transfusion, plasma, albumin, compound amino acids, even essential diet or intravenous total nutrition can be used.