What examination should children lupus nephritis do?

summary

Lupus nephritis, also known as systemic lupus erythematosus nephritis, refers to the patients with renal disease clinical manifestations and renal dysfunction, or only found in renal biopsy with glomerulonephritis lesions. Systemic lupus erythematosus (SLE) is a recognized autoimmune disease. Most of its lesions involve several systems or organs. What should be done in children with lupus nephritis? Next, I'd like to share my views with you.

What examination should children lupus nephritis do?

Urine routine examination of urine composition changes in the diagnosis of lupus nephritis and curative effect observation have important significance. Ln patients may have hematuria, proteinuria, leukocyturia and tubular urine. When the renal function is not complete, the proportion of urine may decrease, and uremia may occur. Urea nitrogen and creatinine are significantly increased.

The ESR of patients with active SLE was almost increased by blood chemistry examination, and the ESR of some patients was still higher even in remission period. The vast majority of patients with active lupus have hyperglobulinemia, mainly due to γ- A few patients had cryoglobulinemia and decreased complement levels (C3, C4, CH50, especially C3); The number of circulating immune complex (CIC) increased, and the number of cytokines such as IL-1, IL-2, IL-6, IL-2 receptor and tumor necrosis factor increased. C-reactive protein is generally not high unless it is associated with infection.

Antinuclear antibody (ANA): the positive rate is 95%, and the specificity is about 70%. It can be used as a good screening test. Peripheral type or homogeneous type is of great significance in the diagnosis of SLE, while spotted type and nucleolar type can be seen in other connective tissue diseases. When ana ≥ 1 / 80, it is quite specific for diagnosis.

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Mutton, dog meat, horse meat, donkey meat, deer meat, etc., due to their warm nature, can not only aggravate the internal heat symptoms of SLE patients after use, but also find that individual patients aggravate the condition of lupus and cause adverse consequences, so it is not suitable for use.