Symptoms of hairy leukoplakia

summary

Hairy leukoplakia is caused by Epstein Barr virus infection, human papillomavirus infection, mixed infection of Epstein Barr virus and human papillomavirus, or human papillomavirus combined with herpesvirus infection. The disease often occurs in the lingual margin. Due to the physiological deficiency of Langerhans cells in this region, the resistance of antibodies in this region is reduced, and it is easy to be invaded by the above viruses. How to treat patients?, What do patients need to pay attention to in their daily life? I have collected some information for you here. Now let's take a look at it together!

Symptoms of hairy leukoplakia

Hairy leukoplakia is an early clinical symptom with high specificity of AIDS. 20% of AIDS patients may have hairy leukoplakia. Hairy leukoplakia is common in the lingual margin, followed by the ventral part of the tongue, dorsal part of the tongue, floor of the mouth, cheek, palate and other parts. The lesions were decolorized leukoplakia, micro uplift, unclear boundary, wrinkled surface, hairy or fibrous, sometimes large plaques adhered to the lingual side, could not be wiped off, and could be accompanied by tongue. No conscious symptoms or mild burning pain.

The serum HIV antibody was positive; The absolute count of peripheral CD4 + cells was significantly decreased, and the ratio of CD4 + / CD8 + cells was low; The smear of lesion site was stained with PAS or cultured, and Candida albicans was positive.

There are hairy processes, hyperkeratosis and dyskeratosis in cuticle, hypertrophy and balloon degeneration in spinous layer, enlargement of cell volume, pyknosis of nucleus, light staining of cytoplasm, and even formation of vacuole cells. There were inflammatory cells infiltration under the epidermis, mainly lymphocytes, a small number of neutrophils and plasma cells. The presence of the virus was confirmed by immunohistochemistry and electron microscopy.

matters needing attention

In daily life, we should pay attention to nutrition, work and rest, keep enough sleep and good mood, help to regulate the immune function of patients, slow down or prevent the progress of the disease. When combined with Candida infection, local or systemic use of anti Candida drugs. Local application of 0.1% tretinoin solution can temporarily eliminate the lesion, but can not prevent recurrence. If HIV positive, according to the principle of AIDS treatment, the system application of effective antiviral drugs.