What are the symptoms of absence seizures?
summary
Absence epilepsy is the most common type of primary generalized epilepsy in children. It is characterized by seizures without convulsive consciousness impairment and generalized spike slow waves of 3-5hz in the background of normal EEG. Because typical absence epilepsy does not show as convulsive seizures, it provides a good opportunity for imaging observation of absence epilepsy. So what are the symptoms of absence seizures?
What are the symptoms of absence seizures?
The clinical symptoms of absence epilepsy are as follows: when the seizure occurs, the consciousness is turbid, the mental disorder, and the mild disturbance of consciousness, only the thinking and reaction become slow, and it is not easy to be found. When there is serious confusion of consciousness, the patient is silent or the language is monotonous, less active, and the directional force is lost, and can also develop into a state of numbness and drowsiness, all mental activities are lost, and the patient only responds to strong stimulation, Some patients had automatism of face, eyelid and hand, lasting for 30 minutes to 12 hours or longer. Absence epilepsy is more common in children, but a considerable part of it occurs in adults. The diseases that need to be differentiated include drug poisoning, mental disorders caused by various reasons, metabolic diseases, complex partial epilepsy, hysteria and some structural brain damage.
EEG plays a decisive role in the differential diagnosis. It is often manifested as continuous or intermittent spike slow wave discharge, which can be regular 3 / s spike slow wave, but more often irregular spike slow wave or multiple spike slow wave discharge of 2-3 / s. EEG changes play a decisive role in the diagnosis. It can not only distinguish epilepsy from psychosis, but also find localized lesions and characteristic EEG abnormalities. In epileptic state, EEG has epileptic electrical activity, namely spike wave, spike slow wave, multi spike slow wave, sharp wave, sharp slow wave, paroxysmal high amplitude slow activity or paroxysmal abnormal discharge on one side.
Recent studies on EEG synchronous functional MRI have found that the thalamus structure may be related to the release of gswd in absence epilepsy, and the functional inhibition of default network areas such as frontal lobe and parietal lobe may be related to the loss of consciousness during absence seizures. Antiepileptic drug therapy is mainly to control the seizure. Sodium valproate and Ethylsuccinate are the traditional first-line drugs for the treatment of absence seizures in children.
matters needing attention
Epilepsies are usually absence seizures, which are more frequent. Clinical treatment should first consider the efficacy and onset time. Because patients need long-term medication, it is also very important to observe its tolerance and safety. Generally speaking, for patients without obvious contraindications or allergic constitution, valproic acid has the advantages of fast onset and good curative effect, so it should be used as the first choice. But if the single drug treatment effect is not ideal, combined application can improve the curative effect.
