What symptom does nephrotic syndrome have repeatedly?
summary
Many nephropathy will start with nephrotic syndrome, because the disease often has complications, such as primary membranous nephropathy, minimal change nephropathy, membranous proliferative glomerulonephritis, focal segmental glomerulosclerosis, mesangial proliferative glomerulonephritis, etc; Secondary purpura kidney, lupus kidney, hepatitis B kidney, diabetic nephropathy, etc. Now let's learn about the repeated symptoms of nephrotic syndrome? It's a matter of time.
What symptom does nephrotic syndrome have repeatedly?
First: as a group of distinctive symptoms, renal syndrome is often misunderstood as an independent disease. It is often judged as nephrotic syndrome according to the large amount of proteinuria and body edema in urine routine, and then anticoagulation, diuresis and hormone therapy are carried out.
Second: the biggest mistake in the treatment is to take the inhibition of urinary protein as the judgment standard. Because the role of hormone is mainly to inhibit the immune inflammatory reaction and reduce the leakage of urinary protein, so the application of hormone, urinary protein will indeed turn negative, for some patients with hormone sensitive constitution, the effect is quite fast.
Third: however, inhibition is not a treatment, which is the reason why proteinuria occurs repeatedly: once the drug is reduced or stopped, the hormone can not inhibit the inflammatory reaction, and proteinuria occurs again. Therefore, we often see patients begin with sufficient hormone, and then reduce the drug bit by bit. As a result, some inducements, such as cold, fever and fatigue, lead to urinary protein again.
matters needing attention
1. Long term use of glucocorticoids can cause disorders of water, salt, sugar, protein and fat metabolism, resulting in adrenocorticotropic hyperfunction. It is characterized by centripetal obesity, resulting in calcium absorption disorder, osteoporosis, and spontaneous fracture in severe cases. 2. Glucocorticoids can weaken the body's ability to defend against diseases, which is conducive to the growth and proliferation of bacteria, and induce or aggravate infection. 3. Glucocorticoid can promote protein decomposition, delay the formation of granulation tissue, and hinder the healing of trauma or surgical wounds and other ulcers. 4. Glucocorticoid has anti growth hormone effect. Long term application of glucocorticoid in children can inhibit bone growth and protein synthesis, and affect growth and development. Application of glucocorticoid in pregnant women can also cause fetal malformation.