How is 10 months old baby liver big to return a responsibility?
summary
Liver enlargement is naturally an abnormal thing. When you mention liver disease, you may be associated with hepatitis B, liver cirrhosis, fatty liver disease, liver cancer, alcoholic liver disease and other diseases. But this "liver disease" is not that "liver disease", what this article said is "infant liver disease syndrome". So how is 10 months old baby liver big to return a responsibility? Let's take a look at it.
How is 10 months old baby liver big to return a responsibility?
First, structural abnormalities of intrahepatic and extrahepatic bile ducts, such as congenital extrahepatic biliary atresia, Alagille syndrome, congenital intrahepatic bile duct dilatation, etc. Biliary atresia is the most common cause, the natural mortality rate is 100%, accounting for 1 / 3 of all causes, and early gexi operation can improve the prognosis.
Second: infection: including primary liver infection and systemic infection involving the liver. Such as maternal viral infection during pregnancy, taking drugs, or having a history of premature delivery, premature rupture of membranes, etc., postnatal children have infections such as omphalitis, buttock inflammation, respiratory tract, digestive tract infection, etc., the main pathogen is viral infection.
Third: congenital genetic and metabolic defects: congenital metabolic abnormalities often involve the liver, but only a few will cause serious persistent liver damage. for example α 1-antitrypsin deficiency, galactosemia, tyrosinemia, hereditary fructose intolerance, hepatic glycogen accumulation, progressive familial intrahepatic cholestasis, Niemann Pick's disease (type C) and Gaucher's disease (infant type) etc.
matters needing attention
1. Lidan Tuihuang: Traditional Chinese medicine can be used to Lidan Tuihuang (Yinchen, Dahuang, Shanzhi). In addition, ursodeoxycholic acid can widely treat cholestasis with mild adverse reactions. 2. Protect liver and improve liver function: some diammonium glycyrrhizinate with remarkable effect of reducing enzyme and stabilizing reduced glutathione of liver cell membrane can be used. 3. Nutritional support treatment: fat malabsorption in cholestasis leads to nutrient deficiency. Replacement of milk powder rich in medium chain fatty acids can improve growth. In addition, some genetic metabolic diseases require special formula. Pay attention to supplement nutrients, including vitamin A, D, e, K and trace elements. Severe children are prone to coagulation dysfunction and hypoproteinemia, and need to be given albumin and coagulation factors. 4. Appropriate anti infective drugs should be used in case of infection.
