Side effects of taking anticancer drugs

summary

Anticancer drugs can be divided into western medicine and traditional Chinese medicine according to their therapeutic characteristics. Western medicine includes chemotherapy and biological targeted therapy, while traditional Chinese medicine includes commonly used prescriptions and Chinese patent medicines. My aunt took oral anticancer drugs after her cervical cancer operation last night, but her memory was not good. I checked the information to understand the side effects of anticancer drugs, and shared it with you....

Side effects of taking anticancer drugs

As long as chemotherapy, side effects are almost inevitable. As with efficacy, toxicity is usually dose-dependent. Increase the dosage, improve the curative effect and increase the toxicity. To a great extent, the success of chemotherapy depends on how to solve the relationship between efficacy and toxicity. Different individuals may have different absorption, distribution, metabolism and excretion of drugs, so we should closely observe and monitor each person.

·1. Physical weakness: patients may have fatigue and weakness, mental depression, sweating, drowsiness, etc. ·2. Decline of immune function: chemotherapy drugs can damage the immune system of patients, leading to the defect or decline of immune function. Immune function indexes such as E-rosette test, CH50, C3 complement, T cell subsets, NK cell activity, IL-II After chemotherapy, it was lower than that before chemotherapy. Bone marrow suppression: most chemotherapy drugs can cause bone marrow suppression, such as the decrease of white blood cells and platelets, and even the decrease of red blood cells and hemoglobin.

·4. Digestive disorders: loss of appetite, reduced diet, nausea, vomiting, abdominal distension, abdominal pain, diarrhea or constipation, etc. Many chemotherapy drugs cause the above symptoms by stimulating gastrointestinal mucosa. ·5. Inflammatory reaction: fever, dizziness, headache, dry mouth, sore mouth, etc. ·6. Cardiotoxicity: some chemotherapy drugs can produce cardiotoxicity, damage myocardial cells, patients with palpitation, chest tightness, precordial discomfort, shortness of breath and other symptoms, and even heart failure. ECG examination can show T wave changes or S-T segment changes.

matters needing attention

·7. Nephrotoxicity: some high-dose chemotherapy drugs can cause renal function damage, such as low back pain and renal discomfort. ·8. Pulmonary fibrosis: cyclophosphamide, vincristine, and bleomycin can cause pulmonary fibrosis. Chest X-ray shows that the lung texture is thickened or changes in strip shape. It is more dangerous and even life-threatening for patients with poor pulmonary function in the past. ·9. Phlebitis: the vast majority of chemotherapy drugs are administered by intravenous drip, which can cause phlebitis of different degrees. The color of diseased blood vessels turns to dark red or dark yellow, with local pain and cord shape. Severe cases can lead to thrombophlebitis, blood flow obstruction. ·10. Nervous system toxicity: mainly refers to the damage effect of chemotherapy drugs on peripheral nerves, patients may have limb numbness, limb insensitivity, etc. Such as vincristine, vinorelbine, vinorelbine, Navelbine and so on can appear different degrees of neurotoxicity. ·11. Hepatotoxicity: almost all chemotherapy drugs can cause liver function damage, mild cases may have abnormal liver function, and patients may have liver discomfort. Even can cause toxic hepatitis. ·12. Cystitis: ifosfamide, cantharidin, camptothecin, etc. can make the patient have a series of drug-induced cystitis symptoms such as abdominal discomfort or pain, hematuria, etc.