What are the side effects of taking debagin for a long time

summary

My friend has been taking debarkin because of epilepsy. Although I know that long-term medication will definitely bring some side effects, I still want to find out what kind of impact it will have. Let's talk about the side effects of taking debarkin for a long time.

What are the side effects of taking debagin for a long time

First: neurological disorders: during the treatment of sodium valproate, a small number of patients have drowsiness or numbness, and lead to transient coma (encephalopathy). During the treatment, they can appear alone or at the same time with epileptic seizures. When the dosage is reduced and stopped, these symptoms will be reduced. These cases are often found after combined treatment, especially with phenobarbital or sudden increase of the dosage of valproate.

Second: digestive tract disorders (nausea, stomachache) often appear at the beginning of treatment, but do not need to stop treatment, symptoms can usually disappear in a few days. Transient and / or dose-related adverse reactions have been reported: alopecia, mild postural tremor and drowsiness.

Third: blood system: mostly thrombocytopenia, rare anemia, leucopenia or pancytopenia. Pancreatitis was occasionally reported, sometimes leading to death. Vasculitis has been reported. Simple and mild hyperammonemia without abnormal liver function may occur from time to time, but it does not need to stop treatment.

matters needing attention

Debagin is a drug used to treat epilepsy. If it is taken for a long time, it will affect the blood system, digestive tract and nervous system of the patients. In patients who have received other antiepileptic drugs before, the replacement with debakin should be carried out gradually.