What is the cause of congenital stupidity?

summary

Congenital folly syndrome is also known as children's Down's syndrome. As the name suggests, congenital folly syndrome refers to children's congenital mental retardation. We all know that congenital folly syndrome is caused by children's chromosomal abnormalities. In order to fully understand the etiology of congenital folly syndrome, let me introduce it in detail.

What is the cause of congenital stupidity?

First: 1866, Dr.John Langdon down is the first to describe and publish the typical signs of Down's syndrome, including the similar facial features of children with Down's syndrome. Therefore, the syndrome is named Down's syndrome. In 1959, it was confirmed that Down's syndrome was caused by chromosome abnormality (one more chromosome 21). Modern medicine has confirmed that the incidence of Down's syndrome is related to the pregnant age of the mother. It is an abnormality of chromosome 21. There are three types of Down's syndrome: trisomy, translocation and chimerism. The high age of mother and the aging of egg are the important reasons for non separation.

Second, the non separation of chromosome 21 in parents' germ cells during meiosis leads to trisomy (the child has three chromosomes 21). The mechanism is that the chromosomes of the germ cells of the parents (mostly the mother) do not separate during meiosis. Studies have shown that older pregnant women (high-risk pregnant women) are more likely to have Down's syndrome. But it is not to say that the fetus of high-risk pregnant women must be down's baby; The fetus of low-risk pregnant women must not be down's baby. In the family study of normal diploid parents who repeatedly gave birth to trisomy 21, it was found that the chimeric trisomy 21 cell lines in the parents' germ cells and the single parent disome of maternal chromosome 21 were also the causes of trisomy 21. The translocation type can be inherited by one of the parents who is a balanced translocation carrier of chromosome 21. Except for chromosome translocation, the karyotype of peripheral blood lymphocytes in both parents was normal. The key position of chromosome 21 which produces Down syndrome phenotype is 21q22.1-q22.2. The trisomy 21 which does not include this band does not show Down syndrome.

Third: calcium can regulate neuromuscular excitability and maintain normal cardiac function. Therefore, you should eat more calcium rich foods, such as dairy products, shrimp and so on. Provide sufficient essential fatty acids for children with mental retardation: it is extremely important to provide sufficient essential fatty acids in the diet. It is an indispensable nutrient for the brain to maintain normal function, such as walnut, fish oil, evening primrose oil and so on. The content of essential fatty acids is high, so you can choose to increase it appropriately in the diet.

matters needing attention

Pay attention to low sugar diet for children with mental retardation, because too much sugar, especially refined sugar intake is too much, easy to make brain function appear neurotic or neurasthenia and other disorders, therefore, low sugar diet is appropriate, can effectively prevent the occurrence of children with mental retardation.