How to do relapse reinfusion after unrelated bone marrow transplantation
summary
Bone marrow transplantation can also be called hematopoietic stem cell transplantation. Hematopoietic stem cells are derived from bone marrow cells. Patients can rebuild their hematopoiesis and immune system through hematopoietic stem cells. Now let's talk about the relapse and reinfusion after unrelated bone marrow transplantation.
How to do relapse reinfusion after unrelated bone marrow transplantation
First, patients should do a series of blood and bone marrow examination before transplantation to determine the disease diagnosis, type and disease status, so as to determine the appropriate pretreatment scheme, monitoring of primary disease after transplantation and appropriate intervention strategy. At the same time, normal donors with identical HLA matching should be selected.
Second: the use of pretreatment programs can create space, immunosuppression and disease clearance. Therefore, there are many kinds of pretreatment schemes to choose.
Thirdly, one of the key factors of non myeloablative hematopoietic stem cell transplantation is that the intensity of radiotherapy (chemotherapy) is significantly lower than that of traditional regimen. There are three main sources of hematopoietic stem cells for transplantation: bone marrow, peripheral blood hematopoietic stem cell collection and umbilical cord blood. After proper treatment, it was reinfused to the patients after pretreatment.
matters needing attention
When patients have undergone bone marrow transplantation, they can be divided into three types according to different donors: autologous hematopoietic stem cell transplantation, homogeneic hematopoietic stem cell transplantation, and allogeneic hematopoietic stem cell transplantation. After bone marrow transplantation, patients may have related complications.