What are the genetic causes of vitiligo

summary

Mention vitiligo, many friends will smell the disease color change, my father is a vitiligo patient, but I am normal, now I am pregnant with a baby, many people say, the heritability of vitiligo is very high, but vitiligo is hereditary, but not 100% will be inherited to the next generation, next I will give you an analysis of the genetic causes of vitiligo.

What are the genetic causes of vitiligo

First of all, vitiligo does have a genetic probability. If parents have vitiligo, their children's probability of suffering from vitiligo is higher than that of normal children. Vitiligo is multi locus inheritance. Multi locus inheritance means that parents inherit vitiligo to their children, but vitiligo does not necessarily occur. It needs several factors to cause it.

Secondly, the next generation of people with vitiligo in their families may also get it. Vitiligo has family genetic tendency, vitiligo has family genetic tendency. If there are vitiligo patients in the lineal and collateral lineal range of the third generation of the family, the risk of other members will be higher than that of the normal population. Vitiligo has a certain genetic background, and it has been reported that both monozygotic twins suffer from vitiligo, which suggests that vitiligo may be caused by an autosomal dominant gene abnormality.

Finally, vitiligo is affected by a variety of factors, vitiligo has a family genetic predisposition, family three generations of lineal, collateral range of patients with vitiligo, the risk of other members will be higher than the normal population. Tracing the family history of vitiligo, we found that more than one person in about 15% ~ 20% of the families suffered from vitiligo. Heredity is only a factor in the pathogenesis of vitiligo, but from the perspective of heredity, heredity is only a factor in the pathogenesis of vitiligo. In addition, environmental factors (including lifestyle, work, learning environment, eating habits, mental state, air, water, etc.) also play an important role.

matters needing attention

If parents are patients with vitiligo, their children have genetic risk, so we should pay more attention to that parents should start to care about their children's eating habits, life and study when they are young, so as to combine work with rest, avoid sun exposure, reduce their psychological burden, and the incidence may be greatly reduced. Whether vitiligo is inherited to children, most of them appear after puberty or even middle age, so it is difficult to grasp which members of the family may inherit the disease in the early stage.