How to judge whether it is alcoholic liver disease

summary

One of my friends especially likes to drink. Recently, he had a problem with his body. He told us that he always had abdominal distension and fatigue. I told him that I suspected whether it was alcoholic liver. My brother didn't believe it. I took him to the hospital for examination, and the diagnosis was alcoholic liver. Now let me tell you how to judge whether it is alcoholic liver disease.

How to judge whether it is alcoholic liver disease

First, clinically, patients with mild alcoholic liver disease will have abdominal distension, fatigue, liver discomfort, anorexia, jaundice, hepatomegaly and tenderness, pale complexion, ascites, edema, spider nevus, fever, leukocytosis (mainly due to neutropenia) similar to bacterial spreading infection, and a few have splenomegaly and other symptoms, with serum bilirubin < 100 μ mol / L; In addition to the above symptoms, moderate and severe symptoms included persistent low fever, diarrhea, numbness of limbs, hand tremor, decreased sexual function, erectile dysfunction in men, etc. liver function examination showed moderate increase of AST and alt, and AST / ALT ratio close to 3.

Second: clinically, patients with mild alcoholic liver disease will have abdominal distension, fatigue, liver discomfort, anorexia, jaundice, hepatomegaly and tenderness, dark complexion, ascites, edema, spider nevus, fever, leukocytosis (mainly neutrophilia) similar to bacterial spreading infection, and a few patients have splenomegaly and other symptoms, with serum bilirubin < 100 μ mol / L; In addition to the above symptoms, moderate and severe symptoms included persistent low fever, diarrhea, numbness of limbs, hand tremor, decreased sexual function, erectile dysfunction in men, etc. liver function examination showed moderate increase of AST and alt, and AST / ALT ratio close to 3.

The third is biochemical examination: serum bilirubin and AST / ALT ratio may be increased, that is, AST activity is significantly increased, while ALT activity is only slightly increased or normal. When AST / ALT > 2, the sensitivity, specificity and positive predictive value were 68%, 91% and 82% respectively. The activity of serum GGT is helpful to the detection of alcoholic liver disease. Its value is not that it has specificity, but that it is significantly increased when a large amount of alcohol intake and / or alcoholic liver disease. In other words, simultaneous determination of MCV, GGT and alkaline phosphatase may be an ideal routine joint laboratory test for the diagnosis of alcoholic liver disease.

matters needing attention

Everyone drinks a lot. It's good for me to drink a little or two at ordinary times, but it's bad for me to drink more. Usually should do some sports, such as mountain climbing, running and other outdoor sports. Regular diet, three meals a day on time to eat, can not take wine as a meal to eat, eat more fruits and vegetables. If you don't feel well, you'd better go to the hospital for a comprehensive examination.