What is spina bifida
summary
Breeding new life is an arduous and great project. If the foundation is not laid well, there will be many crises in the future. The lack of folic acid in the first trimester of pregnancy can cause neural tube malformation in the newborn. If pregnant women in early pregnancy infected with influenza virus, fever, improper use of drugs, strong radiation, will affect the closure of neural tube, spina bifida. What is spina bifida? Let's talk about it.
What is spina bifida
First: spina bifida refers to the deformity of congenital incomplete spinal canal closure, which forms a gap in the back or ventral side of the spine, and can be accompanied or not accompanied by protrusion of spinal membrane and nerve components. Spina bifida is a congenital malformation with abnormal neurospinal fusion. It occurs after the third to the fourth week of pregnancy. When the patient is born, there are often cracks in the lumbosacral bone, and the meningocele can be seen visually. Even for the invisible patients, the spinal fluid leaks due to spina bifida. About 70% of the patients are born with hydrocephalus.
Second, the development of chondrogenic center or osteogenic center in embryonic stage is obstructed, so that the bilateral vertebral arch does not fuse at the back and form a gap of different width. Spina bifida occulta is more common in patients with simple bony cleft, while spina bifida occulta is more common in patients with meningocele or myelocele.
Third: scientific research found that in the first four weeks of pregnancy, if pregnant women obviously lack folic acid, it may lead to fetal neural tube abnormalities, and eventually lead to serious consequences, one of the consequences is to cause spina bifida, resulting in serious dysfunction. This fully shows the importance of folic acid intake during pregnancy. Women planning to get pregnant should start taking folic acid before pregnancy.
matters needing attention
In order to take effect when the fetal neural tube is closed, folic acid should be supplemented from 3 months before pregnancy to the end of the third month of pregnancy, 0.4 mg per day. If the supplement is excessive, it may cause fetal zinc deficiency, growth restriction and other problems.