How is alveolus protein deposit disease to return a responsibility?

summary

Pulmonary alveolar proteinosis (Pap) is also called Rosen Castle man Liebow syndrome. The pulmonary alveoli and bronchioles were filled with PAS positive and phospholipid rich protein from the lung. Most of them are young and middle-aged. The etiology is unknown, which may be related to immune dysfunction (such as thymus atrophy, immune deficiency, lymphopenia, etc.). Dust, especially in animals exposed to silica dust, can cause PAP. It is suggested that the nonspecific reaction to some stimulants may lead to the decomposition of alveolar macrophages and the production of PAS positive protein. Now let's talk about pulmonary alveolar proteinosis?

How is alveolus protein deposit disease to return a responsibility?

1. Such as a large amount of dust inhalation (aluminum, silicon dioxide, etc.), decreased immune function (especially in infants), genetic factors, alcoholism, microbial infection, etc. For infection, it is sometimes difficult to confirm whether it is the primary pathogenic factor or secondary to pulmonary alveolar proteinosis. For example, cytomegalovirus, Pneumocystis carinii and histoplasmosis were found to have high protein deposition in alveoli.

2. Most of the cases are insidious. The typical symptoms are shortness of breath after activities. Later, when they progress to rest, they also feel shortness of breath, cough white or yellow sputum, fatigue and emaciation. Secondary infection, fever, purulent sputum. A few cases may be asymptomatic, only X-ray abnormal performance. Respiratory dysfunction worsened with the development of the disease, and dyspnea with cyanosis also became more serious.

3. The chest X-ray findings were diffuse, marginal, fuzzy and small nodular shadows scattered from the bilateral pulmonary hili, often fusing into flakes. There were compensatory emphysema or small transparent areas between the lesions. 　　

matters needing attention

High protein content and rich amino acids are beneficial to supplement hypoproteinemia caused by alveolar protein deposition. Rich in protein and calcium, it can increase the function of alveoli and reduce the exudation of protein. Protein rich, iron and calcium are also very rich, conducive to increasing lung function.