What is hypergastrinemia?

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summary

Gastrin is an important gastrointestinal hormone, which is mainly secreted by G cells. G cells are typical open cells, most of which are located in antrum, followed by fundus, duodenum and jejunum. D cells of human islets can also secrete gastrin. What is hypergastrinemia? Next, I'd like to share my views with you.

What is hypergastrinemia?

Hypergastrinemia: seen in gastrinoma, excessive formation of gastric antrum mucosa, residual gastric antrum, chronic renal failure. After the recovery of renal function, gastrin levels mostly returned to normal,

If cannot restore, often prompt to have the possibility of atrophic gastritis. Hypogastric acid or no acid hypergastrinemia: seen in gastric ulcer, type a atrophic gastritis, after vagotomy, hyperthyroidism.

Abnormal increase of fasting gastrin concentration and abnormal gastrin response to meal stimulation in patients with peptic ulcer are important mechanisms of peptic ulcer in children. Fasting hypergastrinemia is one of the characteristics of duodenal ulcer in children, which is different from that in adults.

matters needing attention

Diet: eat less and eat more. Less food can shorten the time of stimulating gastric acid secretion, reduce the expansion of gastric antrum and the secretion of gastrin. More meals, 4-5 times during the day. Try to adapt the food to the habits of the sick children, low-fat, moderate amount of protein and carbohydrate. Fried, spicy food should be taboo.