How does purpura nephritis anhydride muscle low return a responsibility?

summary

Creatinine is one of the most important examination items in the process of renal function examination. Whether the creatinine is low or high, patients should pay high attention to it. So what's going on with low creatinine? According to hospital experts, when the results of urea nitrogen and creatinine in renal function examination are lower than the normal value, they generally have no clinical significance. How does purpura nephritis anhydride muscle low return a responsibility? Let's talk about it

How does purpura nephritis anhydride muscle low return a responsibility?

Serum creatinine is the most commonly used index to detect renal function, and it is also a necessary item for physical examination. Many examinees, when their serum creatinine value is within the normal range, think that their renal function is completely OK. In fact, this is a misunderstanding of serum creatinine. Because the serum creatinine value can not reflect the renal function timely and accurately. When the majority of human kidneys suffer from pathological damage and the decrease of glomerular filtration rate is large (more than 50%), the increase of serum creatinine may appear in clinic. Therefore, the misconception that "normal serum creatinine means nothing to the kidney" should be corrected. If usually vegetarian or thinner, small muscle size, blood creatinine can be low, need to strengthen nutrition. How is creatinine low to return a responsibility? The reason that creatinine is low, what meaning is creatinine low? Attention should be paid to patients with low or high serum creatinine. Creatinine in human body is mainly produced by creatine metabolized by muscle, which is excreted to the body through kidney.

In general, due to the relative stability of the body's muscle mass, the production of creatinine is also constant. The level of serum creatinine mainly depends on the amount of creatinine excreted by the kidney. The compensatory function of the kidney is very powerful. If both kidneys are normal, as long as one kidney functions, serum creatinine can be maintained at a normal level. That is to say, when the degree of kidney damage accounts for more than half of the whole kidney, it will cause the increase of serum creatinine.

When the serum creatinine value is high, it indicates that the patient's renal function has problems, the ability of renal metabolic waste is decreased, and some harmful toxins in the body can not be normally discharged from the body. What about the opposite? The reason of low serum creatinine is that after the kidney is invaded by various causes, it forms pathological changes, stimulates the fibroblasts in the kidney to transform into myofibroblasts, and at the same time invades and stimulates the inherent normal renal tissue, causing the same pathological changes.

matters needing attention

There is no clinical significance when the creatinine is low. There is no need to worry about it. The creatinine in the human body is mainly produced by creatine metabolized by muscles, which is excreted to the body through the kidney. In general, because the body's muscle mass is relatively stable, the production of creatinine is also constant. The level of serum creatinine mainly depends on the amount of creatinine excreted by the liver, If both kidneys are normal, as long as one kidney is functioning, serum creatinine can be maintained at normal level. That is to say, if the degree of kidney damage is more than half, serum creatinine will rise