What are the causes of psoriasis
summary
Psoriasis is a kind of skin disease that is difficult to treat. This disease has a great impact on the life of patients, so when you see patients with psoriasis, we should pay more attention to them, because no one wants to suffer from this kind of skin disease. So, what are the causes of psoriasis? Now I'll popularize it with you.
What are the causes of psoriasis
One of the reasons: heredity: about 30% of the people who have a family history reported abroad, and about 10-17% of the people who have a family history reported in China, are considered to be autosomal dominant inheritance with incomplete penetrance, or autosomal recessive inheritance or sex linked inheritance. Psoriasis is also related to race. It is reported that the incidence rate of black race is low. At present, it is believed that psoriasis is controlled by polygenes and also by environmental factors.
The second reason: metabolic disorder: in the past, it was suspected that the occurrence of psoriasis was related to the disorder of metabolism, protein metabolism, glucose metabolism, vitamin deficiency, sulfur and / or inorganic salt metabolism. Recent studies have shown that the content of camp (cyclic adenosine monophosphate) in psoriasis epidermis is significantly lower than that in normal epidermis, while the content of cGMP (cyclic adenosine monophosphate) is higher. The latter can promote the proliferation of cells, which makes the epidermal cells out of control. Immune dysfunction: more and more studies have shown that immune factors play an important role in the pathogenesis of psoriasis. The activation of dermal vascular endothelial cells, the aggregation of mononuclear cells, the expression of cytokines and adhesion factors, and the induced excessive proliferation of keratinocytes are the key links in the pathogenesis of this disease. Therefore, some people believe that psoriasis is an immune cell disease in essence.
The third reason: infection: clinically, the incidence of some psoriasis and upper respiratory tract infection and tonsillitis and other diseases. When antibiotics or tonsillectomy are used, psoriasis can be improved, especially in patients with acute drop psoriasis. It has also been reported that psoriasis can rapidly worsen and the anti streptococcal o value is also increased after patients are infected with Streptococcus. Therefore, it is believed that the pathogenesis of psoriasis is related to Streptomyces infection. Some people claim that the disease is caused by virus infection. It has been observed that psoriasis may be relieved by antiviral therapy in patients with viral infection. It has been confirmed that there are eosinophilic inclusion bodies in spinous nuclei.
matters needing attention
1. Avoid drinking, drinking strong tea and eating spicy food. Gastrointestinal dysfunction should be corrected. 2. Must insist on medication, can't stop medication because it doesn't itch. 3. Psoriasis patients to often trim nails, infants can wear gloves to prevent scratching. Because there are a lot of bacteria in the nail, once scratch the affected area will make the skin worse because of infection. 4. Psoriasis patients in the process of exercise must pay attention to, such as once the skin damage, may make the disease worse.
