Why does membranous nephropathy get thrombus

summary

My grandfather is membranous nephropathy, has been actively treated, but some time ago there was a phenomenon of thrombosis, we went to the hospital, the doctor said and membranous nephropathy has a certain relationship, so why membranous nephropathy thrombosis? Let me give you a detailed introduction.

Why does membranous nephropathy get thrombus

First, membranous nephropathy has a great impact on the body of patients, found that must be timely treatment, they can come out from the pain of membranous nephropathy, because if the treatment is not timely, it is easy to cause thrombosis. Also need to pay attention to the symptoms of nephrotic syndrome is that patients are prone to thrombosis, especially membranous nephropathy incidence of 25% - 40%. The causes of thrombosis include edema, less activity of patients, venous stasis, hyperlipidemia, increased viscosity due to blood concentration, high fibrinogen content, increased factor V, VII, VIII and X, and hypercoagulability due to the use of adrenocortical hormone.

Second, membranous nephropathy is generally divided into primary and secondary. Regardless of the nature of various manifestations of massive proteinuria, the loss of a large amount of plasma albumin will decrease, and the liquid in the blood vessels will penetrate into the skin and form edema. At the same time, a large amount of plasma albumin is synthesized in the liver, and a large amount of lipids, such as triglycerides, are synthesized. Total cholesterol is released into the blood and blood volume is reduced, Mixed hyperlipidemia, it is easy to form thrombosis.

Thirdly, due to the infection, a large amount of immunoglobulin is lost from the urine, and the plasma protein is reduced, which affects the antibody formation. With the application of adrenocortical hormone and cytotoxic drugs, the patient's systemic resistance is reduced, and infection is very easy to occur, such as skin infection, primary peritonitis, respiratory tract infection, urinary tract infection, and thrombosis is more likely to occur.

matters needing attention

Patients with membranous nephropathy should pay more attention to the diet, the best is a low-fat diet, food selection of low fat, cholesterol content. It is suitable for renal disease patients with renal insufficiency or elevated blood lipid. Seaweed, Porphyra and Auricularia auricula can be used in clinic. Hawthorn, onion, lotus seed, celery, water chestnut, kelp, japonica rice, pasta, etc. High calorie diet, increase the frequency of eating in the diet, increase snacks, sweets, sugars. It is suitable for patients with chronic nephritis and chronic renal failure without diabetes.