Urine creatinine high how to return a responsibility

summary

I went to the hospital for examination this year and found that the urine creatinine was high. Later, after treatment, the symptoms improved a lot. Let me share what happened to the high urine creatinine.

Urine creatinine high how to return a responsibility

First, in the early stage of kidney injury, due to the untimely treatment, the damage is further aggravated, which makes the healthy functional cells of kidney undergo phenotypic transformation.

Second: a series of nephrotoxic cells and growth chemokines, so as to synthesize and secrete a large number of collagen fibrin which is not easy to be degraded.

Third: the dynamic balance mechanism of synthesis and degradation is out of balance, so that a large number of extracellular matrix precipitates and condenses, replacing healthy functional units, resulting in glomerulosclerosis; renal tubular degeneration and atrophy; interstitial tissue, blood vessels and other fibrosis. Due to the gradual reduction of functional units, the irreversible organic damage gradually increases, and the progressive damage of renal function aggravates.

matters needing attention

Generally speaking, although the patients with renal insufficiency and azotemia have high creatinine and begin to have various mild clinical symptoms, due to moderate pathological damage, we can control the intake of salt and give them low salt or no salt diet according to the presence or absence of hypertension and edema.