What is the symptom of dermatomyositis
summary
Dermatomyositis is a kind of non suppurative inflammatory disease mainly involving striated muscle and lymphocyte infiltration, with or without a variety of skin lesions. Clinically, it is characterized by symmetrical weakness of limb girdle muscle, neck muscle and pharyngeal muscle, often involving multiple organs, and may also be accompanied by tumor and other connective tissue diseases. What is the symptom of dermatomyositis? Let's talk about it
What is the symptom of dermatomyositis
Muscle involvement is usually bilateral symmetry. Scapular band and pelvic band muscle involvement is the most common, followed by neck muscle and throat muscle. Respiratory muscle involvement is rare, orbicularis oculi muscle and facial muscle involvement is rare. About half of the patients had myalgia and / or tenderness.
About half of the patients suffered from cervical muscle involvement, especially the cervical flexor muscle. It was difficult to raise the head when lying on the back, and it was unable to raise the head when sitting; Pharyngeal or upper esophageal rhabdomus involvement may lead to dysphagia, hoarseness and dysphonia. When ingesting liquid food, it may flow out through the nostril and cause cough.
Cardiac involvement is common, generally mild, with few clinical symptoms. The most common is arrhythmia, such as palpitation, arrhythmia. Congestive heart failure may occur in late stage, which is caused by myocarditis or myocardial fibrosis. Occasional myocarditis. The myocardial isoenzyme of CK may be increased, but it is not necessarily related to myocardial involvement. Most of them are produced by regenerated myofibrils of damaged muscle.
matters needing attention
Glucocorticoid is the first choice in the treatment of polymyositis and dermatomyositis because of its reliable efficacy. Light can be taken orally in the morning, the best three times for heavy, once the disease is under control, and then changed to an oral. Generally, the course of treatment should not be less than 2 years, and the drug can be stopped at last. If there is no recurrence in 3 years, it is unlikely to recur later. If there is no recurrence in 5 years, it is basically cured.