Genetic risk of cleft lip in infants

summary

Cleft lip and palate is not formed after birth, but a kind of defect that children will have when they are born. Normal people have two upper and lower lips. Cleft lip and palate children have three or four lips when they are born, and can also be accompanied by cleft palate. It is not only not good-looking in appearance, but also seriously affects eating and drinking. Since there are defects before birth, there are two reasons. On the one hand, the parents have genetic defects, which are passed on to their children. On the other hand, when the mother is pregnant, she is affected by the external bad environment, such as infection, drinking, smoking, taking medicine and so on. Next, I'll tell you about the genetic probability of cleft lip caused by taking medicine.

Genetic risk of cleft lip in infants

First, there is an important relationship between cleft lip and palate and heredity. At present, no independent gene has been found to be related to cleft lip and palate. The formation of cleft lip and palate is caused by a variety of gene defects. Cleft lip and palate can appear alone, but also as a manifestation of a variety of congenital defects. The probability of cleft lip caused by taking medicine is relatively higher. Please note that the probability is that there is this possibility, which is not inevitable. You can check whether you have cleft lip by B-ultrasound at the time of prenatal examination.

Second: about one or two out of 1000 people have cleft lip and palate. If the father or mother is a patient with cleft lip and palate, the probability of children with cleft lip and palate will be significantly higher than the incidence of cleft lip and palate in the population. Moreover, the incidence of children is higher when the father is a patient than when the mother is a patient.

Third: if a child has cleft lip and palate and wants to know whether it is caused by heredity, you can go to the hospital to test the chromosome. When the chromosome is uncertain, you can also choose in situ fluorescence hybridization, or even more advanced sequencing, chips and so on. However, the more high-end technology is, the more expensive it is.

matters needing attention

It should be emphasized that although heredity plays an important role in cleft lip and palate, the relationship between environment and cleft lip and palate can not be ignored, so we should pay attention to the body when we are pregnant, even if we have a cold, we can not use drugs at will, because some drugs are harmful to children, and bad living habits such as smoking and drinking should be given up when we are preparing for pregnancy.