Is renal function normal in hypertensive nephropathy?

summary

Renal hypertension is mainly due to renal parenchymal lesions and renal artery lesions caused by increased blood pressure, diet should also pay special attention, in symptomatic hypertension known as renal hypertension. So, let's take a look first. Is renal function normal for hypertensive nephropathy? Let's introduce the related knowledge of the field.

Is renal function normal in hypertensive nephropathy?

First, the occurrence of this disease is mainly due to glomerular vitreous degeneration, interstitial tissue and connective tissue hyperplasia, renal tubular atrophy, renal arteriole stenosis, resulting in both substantial damage to the kidney and insufficient blood supply; In the middle layer of the renal artery wall, mucinous muscle fibers proliferated, forming most of the small aneurysms, which made the inner wall of the small renal artery protrude like beads, resulting in segmental stenosis of the renal artery; Nonspecific Takayasu arteritis causes renal hypoperfusion. Under the comprehensive effect of the above factors, it leads to the occurrence of hypertension. And hypertension will cause kidney damage, the two promote each other, will make the disease further development. Therefore, we should actively treat renal hypertension.

Second, after renal parenchyma damage, the ability of kidney to deal with water and sodium is weakened. When the intake of sodium exceeds the excretion capacity of the body, there will be water and sodium retention. * water and sodium stay in blood vessels, which can expand blood volume and cause hypertension. At the same time * water and sodium retention can increase the content of sodium and water in vascular smooth muscle cells, increase blood vessel wall thickness, decrease elasticity, increase blood vessel resistance and enhance catecholamine reaction.

Third: the pathogenesis of renal artery stenosis, renal perfusion pressure reduction and renal parenchymal diseases, as well as cell tumors secreting renin, can make the parabulbar cells release a large amount of renin, resulting in increased activity of angiotensin II, systemic arteriole wall contraction and hypertension. Renin and angiotensin II can also increase the secretion of aldosterone, resulting in * retention of water and sodium, increasing blood volume and increasing hypertension. Because the release of kallikrein and prostaglandin is reduced after renal parenchyma damage, the decrease of vasodilators is also an important factor in the formation of hypertension.

matters needing attention

For patients with high blood pressure, antihypertensive drugs are never away from the hand, but the sphygmomanometer should also be away from the body. Especially for patients with unstable blood pressure, it is recommended to measure their blood pressure 2-3 times a day to observe their blood pressure changes in the morning, middle and evening, so as to avoid cardiovascular and cerebrovascular accidents caused by sudden rise of blood pressure. There are many measures that can be used to regulate blood pressure in life, such as medical equipment, diet, mood, etc., which have a great impact on the condition of hypertension.