Symptoms of interstitial nephritis

summary

In clinical practice, some patients with kidney disease are very closely related to their long-term bad eating habits. If patients feel unwell, they should go to the hospital immediately for diagnosis and treatment. Among them, the incidence of interstitial nephritis is a typical representative. Today, let me learn about the symptoms of interstitial nephritis.

Symptoms of interstitial nephritis

First, it is generally a small amount of low molecular weight proteinuria, the quantitative urine protein is mostly 0.5-1.5g/24h, rarely > 2G / 24h; Urine sediment examination can have microscopic hematuria, white blood cells and tubular urine, occasionally eosinophils. Renal tubular dysfunction varies according to the location and degree of the involved tubules, including renal diabetes, renal tubular acidosis, hypotonic urine, and Fanconi syndrome.

Second, some patients may have hypokalemia, hyponatremia, hypophosphatemia and hyperchloremic metabolic acidosis. Hematuric acid is usually normal or slightly elevated. The incidence of anemia in chronic interstitial nephritis is high and the degree is serious, which is often positive cell and positive pigment anemia. The proportion of eosinophils in peripheral blood of patients with acute interstitial nephritis is increased, which may be accompanied by increased IgE. Idiopathic interstitial nephritis may have anemia, increased eosinophils, rapid ESR, increased CRP and globulin.

Third: acute interstitial nephritis B ultrasound can show the normal size or volume of the kidney increased, cortical echo enhancement. B-ultrasound, radionuclide, CT and other imaging examinations of chronic interstitial nephritis usually show that both kidneys are shrunk and the contour of kidney is not smooth. Imaging examination can also help to determine some special causes, such as urinary tract obstruction, vesicoureteral reflux, renal cystic disease, etc. Intravenous urography can show the characteristic signs of renal papillary necrosis in painkiller nephropathy. Because of the toxicity of contrast medium to renal tubules, it should be used with caution when renal tubules are injured.

matters needing attention

The overall evaluation of human immune function can make clear the diagnosis of kidney disease, evaluate the severity of the disease, detect the degree of renal function damage, evaluate the prognosis of kidney disease and treatment effect.