What is narcolepsy

summary

Recently, I always feel that I can't sleep enough. I go to bed early every night and get up late in the morning. I sleep 12 hours a day, but I always feel sleepy. I go to see a doctor and say that I have narcolepsy, which makes me puzzled. Today, let me learn from you what narcolepsy is.

What is narcolepsy

First: narcolepsy is a sleep disorder characterized by paroxysmal irresistible sleep during the day. According to the statistics of the narcolepsy research center of Stanford University, the prevalence of narcolepsy in the United States is more than 0. 05%。 The prevalence in Western European countries is about 0. 02%~0。 The prevalence rate was 0.06%. 16%~0。 18%。

Second, the etiology is not clear, which may be related to the decreased function of the ascending activation system of the brainstem reticular formation or the hyperfunction of the caudal pontine reticular nucleus. There are also studies that it is an autosomal dominant genetic disease. Although the incidence is high in some ethnic groups, such as Japanese, cases have been reported in various ethnic groups and all over the world.

Thirdly, the genetic characteristics of HLA in various populations are closely related to the minimal HLA tissue related genes (DR and DQ loci). The pathogenesis is the disorder of REM sleep regulation and the loss of control of REM sleep following NREM sleep cycle. Whether at the beginning of sleep or during the waking period, the tendency to enter REM sleep increased.

matters needing attention

Narcolepsy has no great harm to life, but it often affects life, study and work. Special attention should be paid to accidental injuries and accidents. The disease course is very long, and the symptoms can exist for life, but with the increase of age, the attack decreases, and the symptoms are alleviated.