How long does sibelium take effect commonly?
summary
Many people due to overwork or mental tension, will appear dizzy phenomenon, some patients even appear general weakness, numbness of hands and feet phenomenon, in this case, we have to go to the hospital for examination, to see if it is due to the lack of blood supply to the brain caused by this phenomenon, how long does sibelium generally take effect? Let's talk about it
How long does sibelium take effect commonly?
Sibelium is a kind of chemical drug, which is mainly used to treat cerebral insufficiency, vertebral artery ischemia, after cerebral thrombosis, tinnitus, dizziness and other diseases. It can also prevent migraine, and has adjuvant treatment effect on epilepsy. The common reactions after taking sibelium are drowsiness and fatigue, and long-term users may have depression.
The peak value of plasma was 2-4 hours after oral administration of sibelium, and T1 / 2 was 2.4-5.5 hours. Sibelium was mainly distributed in liver, lung and pancreas, and accumulated in bone marrow and fat. After 5-6 weeks of continuous administration, the stable blood concentration was reached, 90% of which was combined with plasma protein, could pass through the blood-brain barrier, and could be secreted with milk. Most of them are metabolized by liver and excreted by digestive tract. It enters the intestine through bile and excretes through stool.
For central vertigo and peripheral vertigo including vertebrobasilar insufficiency, flunarizine was given 10-20 mg daily for 2-8 weeks. For idiopathic tinnitus, flunarizine 10mg, once a night, 10 days as a course of treatment.
matters needing attention
Please use it at the recommended dose. Doctors should observe patients regularly (especially during maintenance treatment), so as to ensure timely withdrawal of drugs in case of extrapyramidal or depressive symptoms. If the curative effect of maintenance treatment decreases, the treatment should also be stopped.