Recurrent polychondritis with uveitis?

summary

Relapsing polychondritis is a rare autoimmune disease, mainly manifested as inflammation of auricle, nose, throat and trachea cartilage, prone to arthritis, scleritis, scleritis and uveitis. What does that recrudescent sex much cartilage inflammation companion send uveitis specific matter?

Recurrent polychondritis with uveitis?

1. Ocular manifestations: ocular manifestations are the initial manifestations of the disease, but most of them occur after systemic lesions. The incidence of eye diseases is about 50%. The main manifestations are conjunctivitis, scleritis, episcleral keratitis, peripheral ulcerative keratitis, iridocyclitis. In addition, choroiditis, chorioretinitis, neuro ophthalmic abnormalities, optic neuritis, optic disc edema, exophthalmos, extraocular muscle paralysis, eyelid edema, dry keratitis can also be seen.

2. Nonspecific systemic manifestations: patients may have fever, weight loss, fatigue, night sweats, lymphadenopathy and other nonspecific systemic manifestations. Auricular chondritis: auricular chondritis is the most common, accounting for 80% - 90% of the total number of patients. Sudden onset, characterized by unilateral or bilateral auricle swelling and pain, inflammation is easy to relapse or chronic, resulting in cartilage damage, leading to auricle ptosis, or cauliflower like appearance. Because the external ear is covered by the deformed auricle, it can cause hearing loss, serous otitis media, sensorineural hearing loss and vestibular dysfunction.

Uveitis: iridocyclitis is a common manifestation that can occur in 30% of patients. Iridocyclitis is recurrent and easy to cause complicated cataract. It is often accompanied by scleritis, keratitis and retinopathy. Sometimes uveitis can be the initial manifestation of the disease. In addition, there may be posterior uveitis, vitreitis and other inflammation of the posterior segment of the eye.

matters needing attention

Because it is multiple chondritis, there will be complications of other systems. Vasculitis is the most common disease coexisting with RP, including isolated cutaneous leukocyte fragmentation vasculitis and systemic vasculitis involving multiple organs, which can involve various sizes of blood vessels. The most common is large artery involvement, characterized by aortic dilatation, recurrent polychondritis or aneurysm formation; There are also microscopic polyarteritis, leading to skin changes, renal manifestations, hearing and vestibular dysfunction. Timely medical treatment