What is the effect of conjugated estrogen tablets?

summary

Conjugated estrogen. Premarin (conjugated estrogen tablets) is an oral preparation, which contains estrogen mixture extracted from pregnant horse urine and is a water-soluble estrogen sodium sulfate mixture. It is a mixture of sodium estrone sulfate and sodium maleestrone sulfate. It also contains sodium sulfate conjugates, 17 α- Dihydromaleestrone, 17 α- Estradiol and 17 β- Dihydromaleestrone. What is the effect of conjugated estrogen tablets? Let's talk about it

What is the effect of conjugated estrogen tablets?

The estrogen contained in conjugated estrogen tablets plays an important role in the development and maintenance of female reproductive system and secondary sexual characteristics. Estrogen makes uterus, oviduct and vagina grow and develop through direct action. Estrogen, together with other hormones, such as pituitary hormone and progesterone, contributes to breast enlargement by promoting mammary duct growth, matrix development and fat synthesis.

Studies have shown that estrogen compensation therapy can reduce the incidence of fracture in postmenopausal women. Before obvious bone loss, the effect of medication was more obvious, which could delay bone loss for an average of 9 years; The combination of estrogen and progesterone can prevent osteoporosis and increase bone mass.

In the treatment of moderate to severe vasoconstriction, and / or menopause related vulvar and vaginal atrophy, the minimum dose for symptom control must be selected, and the medication should not be continued as far as possible. Vasomotor disease - vulvar and vaginal atrophy 0.625mg per day - 0.3mg-1.25mg per day, or more, depending on individual patient response. The treatment can be carried out without interruption, or according to the patient's individual situation, the periodic scheme (such as 25 days of medication, 5 days of withdrawal) can be used for appropriate treatment. If the drug needs to be stopped or gradually stopped, the interval should be 3-6 months.

matters needing attention

Premarin? Not for pregnant women. Taking estrogen can reduce the quality and quantity of milk. Estrogen can be detected in the milk of mothers taking the medicine. Lactating women should not use estrogen. Long term use of natural or synthetic estrogens can increase the risk of breast, uterus, cervix, vagina, testis and liver cancer in some animal species.