How to diagnose Mycoplasma pneumoniae infection?

summary

Mycoplasma pneumoniae infection is a kind of respiratory disease caused by mycoplasma infection. It has certain infectivity, and generally causes cough, fever and other symptoms. If not treated in time, it will endanger life. But through the correct diagnosis and treatment can achieve the effect of recovery. So, Mycoplasma pneumoniae infection need to do what examination to make a diagnosis? Now let's talk about it.

How to diagnose Mycoplasma pneumoniae infection?

The total number of white blood cells in hemogram is usually within the normal range, but occasionally it can be increased. 25% of the patients had white blood cells more than 10 × 109 / L, a few (25.0-56.0) × 109/L。 The number of neutrophils or eosinophils was slightly increased. Thrombocytopenia. Direct Coombs test was positive. ESR can be increased in the early stage of the disease.

Due to the high nutritional requirements and slow growth of Mycoplasma pneumoniae, the culture method needs to be observed for 10-30 days or longer, which is not helpful for clinical diagnosis. At present, hayflied culture medium recommended by CDC is still used in foreign countries, and Martin culture medium or pig lung digestive fluid based culture medium recommended by Capital Institute of pediatrics is commonly used in China.

Serological method complement binding test: it is a widely used serological diagnostic method for the diagnosis of Mycoplasma pneumoniae infection. Patients with double serum titer increasing by 4 times in acute and convalescent stages, or with single serum titer ≥ 1 ∶ 32, are judged as positive. The sensitivity and specificity were 90% and 94%, respectively. The positive reaction was only found in the first infection, but not in the second infection.

matters needing attention

Each of the above examinations has certain limitations, so it is generally a comprehensive examination to confirm whether it is Mycoplasma pneumoniae infection. Patients should not be over stressed. First of all, we should have a good attitude and actively cooperate with the treatment. Mycoplasma pneumoniae infection generally has a long course of disease. Patients or their families should be prepared psychologically, not in a hurry. Follow the doctor's advice and cure thoroughly.