Fungal encephalitis symptoms?
summary
Fungal meningitis is an inflammation caused by fungal invasion of meninges, which often coexists with infection of brain parenchyma. The incidence rate of fungal infection in central nervous system is increasing as antibiotics, hormones, immunosuppressive drugs, especially large doses and long term applications after organ transplantation, increased AIDS incidence and increased number of animal feeding families. There are pathogenic fungi and opportunistic pathogens causing central nervous system fungal infection. The former includes Cryptococcus neoformans, Bacteroides, Blastomyces dermatitis, paraglomus, Sporothrix schenckii, Histoplasma capsulatum, etc; The latter includes Candida, Aspergillus, zygomycetes, trichosporium, etc. Fungal encephalitis symptoms? Let's talk about it.
Fungal encephalitis symptoms?
1、 General systemic symptoms: 1. Mild to moderate fever and other infection in the early stage, and high fever in the late stage; 2. Meningeal irritation such as neck rigidity and positive Kirschner's sign; 3. Headache, nausea, vomiting, optic nerve papilledema and other intracranial pressure increased performance. In the late stage, the headache was severe, and even convulsions, decancephalic tonic attacks and cerebral hernia appeared.
2、 Nervous system symptoms 1. Multi cranial nerve damage symptoms. When the optic nerve is damaged, the vision is low or even blind. Other oculomotor, abductor, facial and auditory nerves are also easily involved, resulting in corresponding symptoms and signs of nerve damage. 2. Symptoms of brain damage: when the lesions affect the brain parenchyma or / and form granuloma in the brain, there may be drowsiness, restlessness, delirium and other mental symptoms, paralysis and other focal signs, and may be accompanied by intellectual and consciousness disorders, and the serious cases may enter into a coma state.
3、 Double or multiple infection symptoms, such as weak constitution, poor nutrition and decreased immune function, can often be accompanied by new infection of other bacteria or recurrence of previous potential bacteria infection in the body. Common complications include tuberculosis and / or toxoplasmosis, which make the disease more serious and complicated and the clinical manifestations more diversified, and even become an important cause of death, It should be noted and determined in time.
matters needing attention
1. The patients with obstructive hydrocephalus can be treated with intraventricular puncture, irrigation, drainage and administration, but should be carried out alternately with intrathecal administration. 2. In order to prevent and control the complications, we should strengthen the prevention and treatment of respiratory tract, oral and urinary tract infections, and pay attention to early detection and treatment of tuberculosis, toxoplasmosis and other double or triple infectious diseases. 3. The supportive therapy was given a high protein, high calorie, multi vitamin diet, related trace elements and nutritional metabolizers (such as adamet, coenzyme A, coenzyme Q-10, wanshuangli and ATP, etc.) to maintain the balance of water and electrolyte, so as to enhance the physique and disease resistance. 4. Neuroprotective agents such as citicoline, brain polypeptide, GM-1, nerve growth factor and Duxil can be used to reduce and slow down the death and apoptosis of nerve cells.
