What is the cause of thalassemia? Just genetic?

summary

Thalassemia, also known as marine anemia, is a hereditary hemolytic anemia. The disease has a common feature, that is, the human globin gene defect makes the synthesis of globin peptide chain in the patient's hemoglobin decrease or cannot be synthesized, which leads to the disease. After the onset of the patient's hemoglobin composition will change, symptoms can be light or heavy, mostly for the performance of chronic hemolytic anemia. In some countries along the Mediterranean coast, the disease is more common. Let's share with you what causes thalassemia.

What is the cause of thalassemia? Just genetic?

Reason 1: the cause of thalassemia is genetic, so how is it inherited? Generally speaking, the disease is mainly caused by the deletion or mutation of globin gene. There are four kinds of globin peptide chains in human body, one of which can lead to thalassemia.

The second reason: in addition to the family history of the patients, the patients also need to carry out laboratory and other related examinations, and the clinical diagnosis of the disease. Hemoglobin electrophoresis is a necessary condition for the diagnosis of this disease, but the hematological examination after blood transfusion treatment will be different from the actual results.

Reason 3: usually, if both men and women are thalassemia patients, combined with the children born after birth, there is a great probability that they will become severe anemia patients. In order to effectively prevent this disease, blood samples need to be taken for peptide chain detection and gene analysis. If it is confirmed that they and their spouses belong to beta type very mild or mild thalassemia patients, their children will have a quarter of the chance to be completely normal and have a second chance One third of the patients have a chance to become mild anemia, and one fourth have a chance to become moderate or severe anemia.

matters needing attention

Thalassemia patients in daily life to eat some jujube and some peanut skin can play a blood tonic effect, especially in patients with severe thalassemia should pay attention to their own nutrition, more safe than blood transfusion treatment.