How is aplastic anemia caused
summary
In recent years, clinical statistics have found that the incidence rate of aplastic anemia has begun to show an increasing trend. The occurrence of this disease seriously damages the normal life of patients and threatens the life safety of patients. Let's talk about how aplastic anemia is caused.
How is aplastic anemia caused
First: ionizing radiation: X-ray, gamma ray or neutron can pass through or enter cells, directly damage hematopoietic stem cells and bone marrow microenvironment. Long term excessive radiation exposure (such as radiation source accident) can cause aplastic anemia.
Second: drugs and chemicals: these substances can be divided into two categories according to their effects: one is related to the dose of the poison, as long as the dose is large, anyone can have bone marrow aplasia; the other is that when exposed to the therapeutic dose or general dose, it can occasionally cause aplasia in some people.
Third: viral infection: various types of hepatitis virus, EB virus, rubella virus, herpes zoster virus, dengue virus, influenza virus, human immunodeficiency virus, human T-lymphocytic leukemia virus, etc. have been reported to damage bone marrow hematopoiesis, causing aplastic anemia or suppression of bone marrow hematopoiesis.
matters needing attention
Aplastic anemia can be secondary to thymoma, systemic lupus erythematosus and rheumatoid arthritis. Antibodies that inhibit hematopoietic stem cells can be found in the serum of patients with aplastic anemia.
