What examination does thalassemia do

summary

In life or on TV, everyone should have heard of thalassemia. Thalassemia is relatively rare. If you find any anemia, you should go to the hospital for examination to see if you are suffering from thalassemia. Now let's talk about the examination of thalassemia.

What examination does thalassemia do

First: thalassemia can be found by blood routine or bone marrow examination, and then combined with family history. Thalassemia should be distinguished from common anemia, infectious hepatitis and cirrhosis. The clinical manifestations of mild thalassemia and iron deficiency anemia are very similar, often misdiagnosed, and thalassemia patients are often accompanied by jaundice, hepatosplenomegaly and other symptoms, in the examination is often misdiagnosed as cirrhosis or infectious hepatitis, but through further examination can be found.

Second: laboratory examination, severe, peripheral hemogram showed small cell hypochromic anemia, red blood cell size, central light staining area expansion, abnormal target shape, fragmented red blood cells and nucleated red blood cells, stippled red blood cells, polychromatic red blood cells, Ho Chou's body, etc.; reticulocyte normal or increased. The bone marrow showed that the proliferation of red blood cell system was obviously active, with the majority of middle and late erythroblasts. The change of mature red blood cells was the same as that of peripheral blood, and the osmotic fragility of red blood cells was significantly reduced.

Third: light. Laboratory examination: there was slight morphological change in mature red blood cells, the osmotic fragility of red blood cells was normal or decreased, hemoglobin electrophoresis showed that the content of HBA2 was increased (0.035-0.060), which was the characteristic of this type, and the content of HbF was normal. The content of HbF increased significantly, mostly > 0.40, which is an important basis for the diagnosis of severe β - thalassemia. X-ray films of the skull showed that the inner and outer plates of the skull became thinner, the barrier widened, and vertical short hair like bone spurs appeared between the bone cortex.

matters needing attention

The above is what thalassemia needs to do. For your reference, when you find that you have problems, you must see a doctor in time and check carefully to get the best treatment.