Adult T-cell leukemia symptoms?
summary
Adult T-cell leukemia is a special type of lymphocytic clonal proliferative disease, which is directly related to human T-cell leukemia virus I (HTLV - I) infection and occurs in adults. Its lesions mainly occur in peripheral blood lymphocytes, and can also invade bone marrow. Adult T-cell leukemia symptoms? Let's talk about it
Adult T-cell leukemia symptoms?
Almost all patients had lymphadenopathy. Many patients have extensive lymphadenopathy, most of them have retroperitoneal lymphadenopathy, but mediastinal mass is rare. Bone marrow often has leukemic cell infiltration. Other common sites of involvement are lung, liver, skin, gastrointestinal tract and central nervous system.
The median age of the patients was 40 years old. Typical performance is: the onset is very urgent, mainly rapid progress of skin damage, hypercalcemia, or both. There are many kinds of skin lesions, such as scattered tumors, fused nodules, plaques, papules, non-specific erythema and so on. Patients with hypercalcemia often show fatigue, apathy, insanity, polyuria and thirst.
Skin lesions are characterized by erythema, papules and nodules. There may be pulmonary infiltration. In general, there was no hypercalcemia, lymph node enlargement, hepatosplenomegaly and bone marrow infiltration were mild; There was no central nervous system infiltration.
matters needing attention
1. Carry out health education on STD prevention and control. 2. Promote safe sexual behavior and actively promote the use of condoms. 3. To prevent mother to child transmission of HTLV-1 and avoid mother to child feeding, so as to reduce infant infection. 4. When using blood, blood or blood products, it must be strictly tested to avoid unnecessary injection, blood transfusion and use of blood products.