Causes of pancreatitis

summary

Acute pancreatitis (AP) is an inflammatory reaction in which pancreatic enzymes are activated in the pancreas, resulting in self digestion, edema, bleeding and even necrosis of pancreatic tissue. It is characterized by acute epigastric pain, nausea, vomiting, fever and elevated serum trypsin. The severity of the disease is different, and the mild one is mainly pancreatic edema, which is common in clinic. The condition is often self limiting and the prognosis is good. It is also known as mild acute pancreatitis. Severe acute pancreatitis is characterized by severe pancreatic hemorrhage and necrosis, secondary infection, peritonitis, shock and other complications with high mortality. So what are the causes of pancreatitis?

Causes of pancreatitis

First, biliary system diseases. In addition, when the bile duct is inflamed, kinin released by bacterial toxin can activate pancreatic digestive enzyme through the communicating branch of bile duct and pancreatic lymphatic vessel to cause acute pancreatitis. In addition, Ascaris lumbricoides, sphincter of Oddi edema, spasm, fiber stenosis, deformity, tumor can cause the lower end of the common bile duct and pancreatic duct obstruction, leading to chronic pancreatitis. 　　

Second, alcohol or drugs. Long term alcoholism can stimulate the increase of protein content in pancreatic juice, form protein "embolus" and block pancreatic duct; at the same time, alcohol can stimulate duodenal mucosa, make papilla edema and hinder the discharge of pancreatic juice. Some drugs and poisons can directly damage pancreatic tissue, such as azathioprine, adrenocortical hormone, tetracycline, thiazide diuretics, L-asparaginase, organophosphorus insecticides and so on. 　　

Third, infection. Many infectious diseases can be complicated with pancreatitis, and the symptoms are not obvious. After the primary disease is healed, pancreatitis subsides spontaneously. The common ones are mumps, viral hepatitis, infectious mononucleosis, typhoid fever, sepsis, etc.

matters needing attention

Pay attention to regular diet, no smoking and alcohol, no spicy food, don't overeat, enhance immunity, prevent cold.