How does fluconazole treat thrush

Update Date: 2021-08-15 Source: Network

summary

Thrush patients are mostly infants, mainly caused by fungal infection. If the treatment is not timely, it will cause more serious oral diseases. Fluconazole in the treatment of thrush effect is very good, its use also has some to pay attention to, let's talk about fluconazole treatment of thrush how to use.

How does fluconazole treat thrush

First: oral. Disseminated candidiasis, first dose 0. 4G, then 0. 2 g, once a day for at least 4 weeks, and lasted for at least 2 weeks after symptom relief. The first dose was 0. 2 g, then 0. 1 g, once a day, lasting for at least 3 weeks, and lasting for at least 2 weeks after symptom relief. According to the treatment response, the dose can also be increased to 0. 4 g, once a day.

Second: This product belongs to pyrrole antifungal drugs. The antifungal spectrum is wide. Oral and intravenous administration of this product is effective for human and various animal fungal infections, such as Candida infection, Cryptococcus neoformans infection, Malassezia furfur, Microsporum, Trichophyton, epidermis, Blastomyces dermatitis, coccidiosporum, histoplasm capsulatum, Chromobacterium fimbriae, Cladosporium carinii, etc.

Third: the mechanism of action of this product is mainly to highly selectively interfere with the activity of cytochrome P-450 of fungi, thus inhibiting the biosynthesis of ergosterol on the cell membrane of fungi. This product is highly selective to the fungus dependent cytochrome P-450 enzyme. Take this product 0. 5 g for 28 days, it has been proved that it has no effect on the plasma testosterone concentration of men and the steroid hormone concentration of women of childbearing age.

matters needing attention

Different patients in the use of fluconazole should pay attention to the dose, because it has a certain selectivity to the cell. Generally, the effect of oral medication is not as obvious as that of direct application on the wound. Prevention of thrush is also very important, usually pay attention to oral disinfection to prevent fungal infection.