How to treat precocious puberty in girls

summary

Due to the neglect of environment and diet, the incidence of precocious puberty in children is increasing year by year, and some cases of infant precocious puberty caused by milk powder also emerge in endlessly. We must be vigilant. For the harm of precocious puberty, parents should have enough understanding and pay attention to it. Precocious puberty refers to the occurrence of sexual maturity 2.8 standard deviations (SD) earlier than that of normal children. At present, it is considered that precocious puberty occurs before the age of 9. How to treat girls' precocious puberty.

How to treat precocious puberty in girls

First, how to find out whether a child has precocious puberty. Before the age of 8 for girls and 9 for boys, there are secondary sexual characteristics not corresponding to age, such as breast enlargement, pubic hair and axillary hair growth, pelvic widening, etc; The symptoms of precocious puberty in boys are very "hidden". In the early stage, the scrotum and testis are enlarged, followed by the development of pubic hair, seminal vesicle and prostate. However, these parts are relatively private and are not easy to be ignored. When children are found with long beard, Adam's apple and acne, they often go through the middle and late stage. In addition to the second sexual characteristics, growth rate is also an important indicator of precocious puberty. Between the age of 3 and adolescence, children generally grow 4-7 cm a year, and adolescence grows 8-12 cm a year. If your child's height increases faster before puberty, you should see a doctor in time. Suggestion: parents should pay attention to some abnormal signs of their children and seek medical treatment early.

Second: precocious puberty signal girls have precocious puberty often first breast enlargement, breast tenderness, can be both sides of the breast at the same time, but also can be only one side of the breast enlargement, later developed to the other side. Before 8 years old, the baby's reproductive organs did not develop, there will be no secretions, if the mother to the baby bath, see the baby vulva leucorrhea like secretions, while the baby's height growth accelerated, the mother should be careful. If not timely and appropriate treatment, there will be pubic hair, armpit hair and vaginal bleeding in the future. At the beginning of more irregular vaginal bleeding, gradually transition to regular menstruation.

Third: how to treat precocious puberty depends on the disease. The therapeutic purposes of central precocious puberty: ① to inhibit or reduce chronic development, especially to prevent menstruation in girls; ② to inhibit bone maturation, improve the final rise in adulthood; ③ to restore the psychological behavior of the corresponding age. (1) in the treatment of etiology, surgery or chemotherapy should be performed for those caused by tumor. Thyroid preparations should be used to correct thyroid function for those caused by radiotherapy or hypothyroidism. Cortisol hormone therapy can be used for patients with congenital adrenal hyperplasia. (2) drug therapy 1. Gonadotropin releasing hormone analogue (GnRHa) the natural GnRH is a polypeptide of 10 amino acids. At present, several GnRHa commonly used are long-acting synthetic hormones that replace the sixth amino acid in the molecule, i.e. glycine with D-TRYPTOPHAN, D-serine, D-Histidine and D-leucine. Their function is to reduce pituitary gonadotropin stimulation through down regulation The secretion of estrogen makes estrogen return to the level before puberty. 1mg / kg, intramuscular injection once every 4 weeks. After treatment, the sexual development, height growth and bone age maturity of the patients can be controlled. The effect is reversible. If the patients can be treated as soon as possible, the final height in adulthood can be improved. 2. The mechanism of gonadal hormone is to inhibit the secretion of hypothalamic pituitary gonadotropin by high dose of sex hormone feedback. For example, medroxyprogesterone, also known as progesterone, is a derivative of progesterone, which is used for girls with precocious puberty. The daily oral dose is 10 ~ 30mg, and it is reduced and maintained after the curative effect appears. Cyproterone is a derivative of 17 hydroxyprogesterone. It can not only block the sex hormone receptor, but also reduce the release of gonadotropin. The dose of cyproterone is 70-150 mg / m2 per day. The above two drugs can not improve the adult height. It is suggested that mild precocious puberty can be treated with traditional Chinese medicine such as Zhibai Dihuang pill, dayinbu pill and other Decoction; moderate precocious puberty and true precocious puberty can be treated with progesterone and gonadotropin releasing hormone under the guidance of doctors.

matters needing attention

1. Over nutrition is one of the main causes of precocious puberty. To prevent the occurrence of precocious puberty, parents should pay attention to high protein food intake not too much, every meal with meat and vegetables, never meat as a dish. 2. Eat less foreign fast food. Studies have shown that children who patronize foreign fast food more than twice a week and often eat fried puffed food are 2.5 times more likely to have precocious puberty than ordinary children. Therefore, every week limit the baby to eat foreign fast food, with fresh fruit instead of fried snacks. 3. Tonic can promote precocious puberty. Therefore, do not blindly give children royal jelly, bee pollen and other "supplements" or health products to enhance intelligence. If necessary, it should be carried out under the guidance of doctors. 4. Mothers should properly store contraceptives, breast enhancement products, etc. to avoid children's misuse or contact, and do not use adult cosmetics or skin care products for children. 5. Lactating mothers are not allowed to use breast products smeared on the breast to prevent the baby from eating into the body. 6, the baby should eat less off-season vegetables and fruits and food containing additives.