What disease is polymyositis

summary

Now I'm going to tell you that my husband's body is getting worse and worse. I said that he had no more and more symptoms of venereal disease.

What disease is polymyositis

First: polymyositis belongs to inflammatory myopathy. It is a group of syndrome characterized by skeletal muscle interstitial inflammation and muscle fiber degeneration. When the lesion is limited to muscle, it is called polymyositis. If the lesion involves skin and muscle at the same time, it is called dermatomyositis. Although the etiology and pathogenesis of this disease is still not very clear.

Second: but it is generally believed to be related to autoimmune dysfunction, such as some patients with rheumatic fever, rheumatoid arthritis, lupus erythematosus, scleroderma and other autoimmune diseases. Recent studies have confirmed that the abnormality of humoral and cellular immune mechanisms is an important cause of the disease. Specific antibodies, such as anti myosin antibody and anti nuclear antibody, can be detected in the blood of many patients.

Third, there was also a large number of activated T cells, and the ratio of CD4 / CD8 in peripheral blood was increased. In addition, the symptoms of some patients improved or returned to normal after treatment with corticosteroids or other immunosuppressants, which also shows the role of immune mechanism in the pathogenesis. Polymyositis is a group of diffuse muscle inflammatory diseases with unclear etiology, the main clinical manifestations of which are symmetrical weakness of proximal limbs, neck muscles and pharyngeal muscles, muscle tenderness, and increased serum enzymes.

matters needing attention

Polymyositis is an inflammatory disease, can occur in all parts of the body, the symptoms are not very obvious, so many times people are not aware of the disease, to the obvious time to check is a more serious situation.