What are the causes of chromosomal abnormalities

Update Date: 2022-08-11 Source: Network

summary

The chromosome in organism is the basic material of nucleus and the carrier of gene. Chromosomal abnormalities can also be called chromosomal dysplasia. Since the International Conference on chromosome nomenclature in Paris in 1971, more than 3000 species of human chromosomal abnormalities and structural aberrations have been found. At present, more than 100 species of chromosomal diseases have been confirmed. Mental retardation and growth retardation are the common characteristics of chromosomal diseases. What exactly causes chromosomal abnormalities and changes in metabolism need further scientific research.

What are the causes of chromosomal abnormalities

First: physical factors: human beings are in a large radiation environment, including natural radiation and artificial radiation. Natural radiation includes cosmic radiation, earth radiation and radiation of radioactive substances in human body. Artificial radiation includes radioactive radiation and occupational radiation. When the amount of radiation is large, it will cause harm to human body and cause chromosome abnormality.

Second: chemical factors: people will be exposed to a variety of chemical substances in their daily life, some of which are pure natural products, some of which are synthetic chemicals. They will enter into the human body through diet, breathing or skin contact, causing varying degrees of variation of chromatids.

Third: autoimmune diseases: according to relevant studies, autoimmune diseases seem to play a certain role in chromosome non separation. For example, there is a close correlation between the increase of thyroid primary autoimmune antibodies and familial chromosomal abnormalities, which can also be manifested as chromosomal abnormalities in clinic.

matters needing attention

There are also many types of chromosomal abnormalities that can be expressed as familial tendency, which indicates that chromosomal aberrations are directly related to heredity. Therefore, heredity is an important factor of chromosomal abnormalities.